ATI RN
How to Study for ATI Pharmacology Proctored Exam Questions
Question 1 of 5
Warfarin is an anticoagulant that…
Correct Answer: A
Rationale: Warfarin is an anticoagulant medication that works by inhibiting the production of certain clotting factors in the liver, specifically factors II, VII, IX, and X. By doing so, warfarin prevents the formation of new blood clots. It does not have the ability to dissolve existing blood clots, as that function is typically carried out by different types of medications known as thrombolytics. Warfarin is commonly prescribed to prevent and treat blood clots in conditions such as atrial fibrillation, deep vein thrombosis, and pulmonary embolism.
Question 2 of 5
The metabolism of the drug en route from the gut lumen to the systemic circulation.
Correct Answer: B
Rationale: The first pass effect refers to the metabolism of a drug as it passes through the liver before reaching the systemic circulation. When a drug is absorbed from the gut lumen, it first enters the portal circulation where it is transported to the liver. In the liver, the drug may undergo metabolic processes that can reduce the amount of active drug reaching systemic circulation. This process can greatly affect the overall bioavailability and effectiveness of the drug. So, the metabolism of the drug en route from the gut lumen to the systemic circulation is primarily due to the first pass effect.
Question 3 of 5
An unpleasant sensory and emotional experience associated with actual tissue damage:
Correct Answer: C
Rationale: Pain is defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage. It is a complex phenomenon involving both physical and emotional components. Pain serves as a protective mechanism, alerting the body to potential harm or injury, and prompting appropriate responses to prevent further damage. Pain can be acute or chronic, and may vary in intensity, duration, and location depending on the underlying cause. Analgesia refers to the relief of pain, inflammation is the body's response to injury or infection, and irritation typically refers to a mild reaction to something that is uncomfortable or annoying, but not necessarily indicating tissue damage.
Question 4 of 5
An international traveler diagnosed with malaria is admitted to the emergency department and is prescribed mefloquine hydrochloride. The nurse anticipates that which laboratory test will be ordered?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
What agents are used primarily to treat cardiac-related conditions? (Select all that apply.)
Correct Answer: B
Rationale: Drugs that block both alpha- and beta-adrenergic receptors are primarily used to treat cardiac-related conditions. Phentolamine, a nonselective alpha-adrenergic blocking agent, is used to treat extravasation of IV norepinephrine or dopamine and hypertension related to a pheochromocytoma. Alpha1-selective adrenergic blocking agents are used for treatment of hypertension and benign prostatic hyperplasia. The beta-adrenergic blocking agents are used to treat cardiovascular problems (hypertension, angina, migraine headaches) and to prevent reinfarction after myocardial infarction. Beta1-selective adrenergic blocking agents are used for treating hypertension, angina, and some cardiac arrhythmias. The nurse should understand the indications for these agents to ensure safe and effective administration.