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free microbiology test bank questions pdf Questions
Question 1 of 5
Viruses cannot multiply in:
Correct Answer: A
Rationale: The correct answer is A: Artificial nutrient media. Viruses are obligate intracellular parasites, meaning they require living host cells to replicate. They cannot multiply in artificial nutrient media as they lack the cellular machinery necessary for viral replication. Living cells, including human embryonic cells and bacteria, provide the required cellular environment for viruses to replicate. Therefore, options B, C, and D are incorrect as they all contain living cells that can support viral multiplication.
Question 2 of 5
Which of the following proteins are encoded by herpesviruses and required for viral DNA replication?
Correct Answer: A
Rationale: The correct answer is A: viral DNA polymerase. This enzyme is essential for replicating the viral DNA during the herpesvirus life cycle. It catalyzes the synthesis of new DNA strands using the viral genomic template. Ribonucleotide reductase (B) is involved in nucleotide synthesis, but not directly in DNA replication. Neuraminidase (C) is an enzyme found in influenza viruses, not herpesviruses. Thymidine kinase (D) is an enzyme that phosphorylates thymidine, but its role is more related to nucleotide metabolism rather than viral DNA replication.
Question 3 of 5
In which of the following GIT infections, the bacteria adhere to the intestine wall and damage the microvilli:
Correct Answer: A
Rationale: The correct answer is A: Enteropathogenic E. Coli (EPEC). EPEC bacteria adhere to the intestine wall using a protein called intimin, leading to microvilli damage. This attachment disrupts the normal absorption function of the intestine. Summary of why other choices are incorrect: B: Enterohemorrhagic E. Coli (EHEC) primarily causes bloody diarrhea and does not specifically target microvilli. C: Enterotoxigenic E. Coli (ETEC) produces toxins that lead to watery diarrhea but does not directly target microvilli. D: Enteroinvasive E. Coli (EIEC) invades and replicates within intestinal cells, causing inflammatory diarrhea, but does not specifically damage microvilli.
Question 4 of 5
Which of the following have a fecal oral route of transmission?
Correct Answer: B
Rationale: The correct answer is B: Typhoid fever. Typhoid fever is transmitted through the fecal-oral route, meaning the bacteria from an infected person's feces can contaminate food or water and then be ingested by another person. This can lead to infection and illness. The other choices, diphtheria (A), syphilis (C), and spotted fever (D) are not transmitted through the fecal-oral route. Diphtheria is spread through respiratory droplets, syphilis is primarily sexually transmitted, and spotted fever is transmitted through tick bites. Thus, only Typhoid fever aligns with the fecal-oral route of transmission.
Question 5 of 5
A patient working at a pig farm complains about paroxysmal abdominal pain, liquid feces with admixtures of mucus and blood, headache, weakness, fever. Examination of large intestine revealed ulcers from 1 mm up to several cm large, feces contained oval unicellular organisms with cilia. What disease should be suspected?
Correct Answer: A
Rationale: Rationale: The symptoms described are consistent with Balantidiasis, caused by the parasite Balantidium coli. The presence of ciliated oval organisms in the feces is characteristic of this disease. Ulcers in the large intestine are common in Balantidiasis due to tissue invasion by the parasite. Headache, fever, and abdominal pain are typical symptoms. Other choices can be ruled out: B) Amebiasis presents with similar symptoms but usually involves the liver. C) Toxoplasmosis typically presents with lymphadenopathy and flu-like symptoms. D) Lambliasis usually causes watery diarrhea without blood or mucus. Therefore, the correct answer is A: Balantidiasis.