ATI RN
Chemotherapy drugs Questions
Question 1 of 5
Used in the prophylaxis and treatment of infection due to influenza viruses, this drug facilitates clumping of mature virions and their adhesion to infected cells.
Correct Answer: A
Rationale: Amantadine prevents viral uncoating and facilitates clumping of influenza virions, aiding in prophylaxis and treatment.
Question 2 of 5
A patient with AIDS has an extremely high viral RNA titer. While blood is being drawn from this patient, the syringe is accidentally dropped, contaminating the floor, which is made of porous material. The best way to deal with this is to
Correct Answer: D
Rationale: A 10% bleach solution is effective for decontaminating HIV on surfaces, as it inactivates the virus quickly and is practical for porous materials.
Question 3 of 5
One chemotherapeutic strategy used to eradicate the blood-stream form of African trypanosomes is based on the absolute dependence of the organism on
Correct Answer: C
Rationale: African trypanosomes rely heavily on glycolysis for energy, making drugs that target this pathway effective.
Question 4 of 5
Which one of the following enzymes is not unique to parasites?
Correct Answer: B
Rationale: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is present in both parasites and mammals, though its substrate specificity differs.
Question 5 of 5
This drug is the antimalarial agent most commonly associated with causing an acute hemolytic reaction in patients with glucose - 6 - phosphate dehydrogenase deficiency.
Correct Answer: D
Rationale: Primaquine causes hemolysis in G6PD-deficient patients due to oxidative stress on red blood cells.