ATI RN
Chemotherapy drugs Questions
Question 1 of 5
Use of the following antimalarial drug carrys high risk of adverse effect in subjects with G-6-PD deficiency.
Correct Answer: C
Rationale: Primaquine causes hemolysis in G6PD-deficient patients due to oxidative stress.
Question 2 of 5
Emetine is now used only as a reserve drug for amoebiasis because
Correct Answer: C
Rationale: Emetine’s cardiotoxicity limits its use to reserve status for amoebiasis.
Question 3 of 5
After treating intestinal amoebiasis with metronidazole, a course of diloxanide furoate is often advised to
Correct Answer: C
Rationale: Diloxanide furoate eradicates luminal cysts post-metronidazole treatment to prevent recurrence.
Question 4 of 5
Pentamidine + contrimoxazole is the treatment of choice for the following disease
Correct Answer: B
Rationale: Pentamidine + cotrimoxazole is not standard; however, cotrimoxazole alone is used for Pneumocystis pneumonia, and this may be a contextual error. Correct answer adjusted to B based on common use.
Question 5 of 5
The following helminthic disease can be treated by albendazole but not by mebendazole
Correct Answer: D
Rationale: Albendazole treats neurocysticercosis (unlike mebendazole) due to better CNS penetration.