UN volunteers have arrived in Nigeria to assist the locals in aftermath of earthquakes. What drug should they prescribe for individual chemoprophylaxis of malaria?

Correct Answer: D

Rationale: The correct answer is D: Primaquine. Primaquine is used for individual chemoprophylaxis of malaria caused by Plasmodium vivax and Plasmodium ovale. It is effective in preventing the relapse of these malaria species by eliminating the liver forms of the parasites. Chingamin (A) is not a commonly used drug for malaria prophylaxis. Pyrantel (B) is an anthelmintic drug used for treating parasitic worm infections, not malaria. Pyrimethamine (Chloridinum) (C) is primarily used in combination with sulfadoxine for treating uncomplicated malaria, not for chemoprophylaxis.

Correct Answer: B

Rationale: The correct answer is B because filoviruses, such as Ebola virus, require investigation in specifically equipped laboratories with high biological protection due to their high pathogenicity and risk of transmission. This is essential for ensuring the safety of researchers and preventing outbreaks. A: This is incorrect as filoviruses are not the most common cause of gastroenteritis; they primarily cause severe hemorrhagic fevers. C: Filoviruses are not widespread; they are typically confined to specific regions during outbreaks. D: Mass immunization is not used for filoviruses as there is no established vaccine for general prophylaxis.

Correct Answer: A

Rationale: The correct answer is A: Sabouraud's peptone agar. This agar is specifically designed for the isolation of yeast and molds due to its low pH and high sugar content, creating an environment conducive for their growth. Yeast-like fungi thrive in this selective medium, while inhibiting the growth of bacteria and other contaminants. Summary: - Sabouraud's peptone agar is ideal for cultivating yeast-like fungi. - Endo agar is used for isolation of gram-negative bacteria, not fungi. - Milk-salt agar is used for lactobacilli and streptococci, not fungi. - Meat infusion agar is a general-purpose medium for cultivation of a wide range of microorganisms, not specifically for yeast-like fungi.

Correct Answer: B

Rationale: The correct answer is B: Vibrio cholerae. Vibrio cholerae is a comma-shaped rod bacterium that causes high volume watery diarrhea by producing cholera toxin. This toxin leads to the secretion of large amounts of fluid into the intestines. Campylobacter jejuni (A) typically causes bloody diarrhea. Pseudomonas aeruginosa (C) and Proteus mirabilis (D) are not associated with high volume watery diarrhea.

Correct Answer: A

Rationale: The correct answer is A: Clostridium perfringens. This bacterium is an anaerobic, Gram-positive rod that forms terminal spores and produces gas. It is commonly associated with wound infections and gas gangrene. Clostridium botulinum causes botulism and does not typically present with gas production. Bacillus anthracis is an aerobic, Gram-positive spore-forming bacterium causing anthrax. Clostridium tetani causes tetanus and does not produce gas. Thus, based on the characteristics described in the question, Clostridium perfringens is the most likely causative agent.

Correct Answer: C

Rationale: The correct answer is C: cell wall composition. Gram staining differentiates bacteria based on the structure of their cell walls. It classifies bacteria into Gram-positive (thick peptidoglycan layer) and Gram-negative (thin peptidoglycan layer). This differentiation is crucial for identifying bacterial species and guiding treatment choices. Size and shape (choice A) are not specific to Gram staining. Presence of flagella (choice B) is related to bacterial motility, not Gram staining. Genetic material (choice D) is not directly assessed by Gram staining. Overall, the unique composition of the cell wall is the key factor in distinguishing bacteria through Gram staining.

Correct Answer: B

Rationale: Answer B, Infectious mononucleosis, is not caused by enteroviruses. Infectious mononucleosis is primarily caused by the Epstein-Barr virus, a member of the herpesvirus family, not by enteroviruses. Enteroviruses are known to cause diseases such as myocarditis, herpangina, and Boston exanthema. Therefore, B is the correct answer. Myocarditis, herpangina, and Boston exanthema can all be caused by enteroviruses, making choices A, C, and D incorrect, respectively.

Correct Answer: D

Rationale: Interferon delta is not a known type of interferon, making choice D incorrect. Interferon beta is indeed produced by fibroblasts (choice A), interferon alpha by leukocytes (choice B), and interferon gamma by lymphocytes (choice C). Each type of interferon is produced by specific cells in the immune system, contributing to the body's defense against viruses and other pathogens.

Correct Answer: A

Rationale: The correct answer is A because CSF (Cerebrospinal fluid) is the sample used for proving epidemic meningitis. It should be transported at 37°C to maintain its integrity. Blood and nasopharyngeal secretions are not typically used for diagnosing meningitis. Choice B, feces, is unrelated to the diagnosis of meningitis. Choice C, CSF transported at +4°C, is incorrect as it should be transported at 37°C to prevent degradation of the sample. Therefore, A is the correct choice for proving epidemic meningitis due to the specificity of the sample and the proper transport conditions.