Type I interferon is released in response to ___, which is recognized using a pattern-recognition molecule called Toll-like receptor 3.

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Ricci Maternity and Pediatrics NCLEX Question Immunization Questions

Question 1 of 5

Type I interferon is released in response to ___, which is recognized using a pattern-recognition molecule called Toll-like receptor 3.

Correct Answer: D

Rationale: TLR3 recognizes double-stranded RNA, triggering type I interferon release.

Question 2 of 5

A 4-year-old boy presents with chronic granulomatous disease (CGD), confirmed with a nitro blue tetrazolium (NBT) test. Which of the following pathogens could this child still mount a defense against?

Correct Answer: D

Rationale: CGD impairs oxidative burst; Streptococcus is less reliant on this for clearance.

Question 3 of 5

Increase mucus secretion and smooth muscle contraction

Correct Answer: A

Rationale: Trypase and chymotrypsin from mast cells enhance mucus production and smooth muscle contraction to expel parasites.

Question 4 of 5

Potent inducer of apoptosis

Correct Answer: C

Rationale: Fas ligand on cytotoxic T cells binds Fas on target cells, potently inducing apoptosis.

Question 5 of 5

DNA vaccines (tested in mice) use the gene for the immunogenic protein and coat it with what element, which is injected into cells and results in antibody production?

Correct Answer: D

Rationale: DNA vaccines use gold particles to deliver genes into cells, triggering protein expression and antibody production.

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