ATI RN
ATI Capstone Pharmacology Assessment 1 and 2 Questions
Question 1 of 5
Two tests should be monitored for a patient currently on Warfarin. What are those two tests? Select ALL that apply.
Correct Answer: B
Rationale: 1. INR (International Normalized Ratio): INR is the primary test used to monitor the effectiveness of Warfarin therapy. It measures the clotting tendency of the patient's blood in relation to a standard measurement. The INR target range for patients on Warfarin therapy varies depending on the reason for treatment, but typically falls between 2.0 to 3.0.
Question 2 of 5
A patient is in the intensive care unit because of an acute myocardial infarction. He is experiencing severe ventricular dysrhythmias. The nurse will prepare to give which drug of choice for this dysrhythmia?
Correct Answer: C
Rationale: Amiodarone is the drug of choice for treating severe ventricular dysrhythmias, such as those seen in patients with acute myocardial infarction. It is effective in treating both ventricular tachycardia and ventricular fibrillation. Amiodarone works by prolonging the action potential duration and refractory period in cardiac tissues, thereby helping to stabilize the heart's electrical activity. Diltiazem and Verapamil are calcium channel blockers that are not typically used for treating ventricular dysrhythmias. Adenosine is primarily used for treating supraventricular tachycardias.
Question 3 of 5
What is important to monitor when giving the drug Phenytoin?
Correct Answer: D
Rationale: When giving the drug Phenytoin, monitoring urinary pH is important because Phenytoin is known to be excreted by the kidneys. Changes in urinary pH can affect the concentration of Phenytoin in the body. Alkaline urine can increase the excretion of Phenytoin, potentially leading to subtherapeutic levels, while acidic urine can decrease excretion, potentially leading to toxic levels of the drug. Therefore, monitoring urinary pH helps ensure that Phenytoin levels are within the therapeutic range, minimizing the risk of either subtherapeutic or toxic effects. Monitoring for signs of toxicity, such as ataxia, nystagmus, and confusion, is also essential when administering Phenytoin.
Question 4 of 5
Which of the following is a nonsteroidal anti-inflammatory agent with a tendency to produce bone marrow depression?
Correct Answer: D
Rationale: Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its potential to cause bone marrow depression. Bone marrow depression is a serious side effect that can lead to decreased production of blood cells, including white blood cells, red blood cells, and platelets. This can result in an increased risk of infections, anemia, and bleeding disorders. Therefore, phenylbutazone should be used cautiously and under close monitoring to avoid this complication. Aspirin, Colchicine, Ibuprofen, and Acetaminophen are not typically associated with causing bone marrow depression as a side effect.
Question 5 of 5
The patient is prescribed an ACE inhibitor. What primary mechanism of ACE inhibitors will the nurse understand as the therapeutic action?
Correct Answer: C
Rationale: The primary mechanism of ACE inhibitors is to inhibit the production of angiotensin II, a potent vasoconstrictor that also stimulates the release of aldosterone. By inhibiting angiotensin II production, ACE inhibitors decrease aldosterone secretion. Aldosterone is a hormone that plays a key role in regulating blood pressure and fluid balance in the body. Inhibiting aldosterone secretion helps to reduce blood pressure by decreasing sodium and water retention, ultimately leading to vasodilation and lower blood pressure levels.