Two tests should be monitored for a patient currently on Warfarin. What are those two tests? Select ALL that apply.

Correct Answer: B

Rationale: 1. INR (International Normalized Ratio): INR is the primary test used to monitor the effectiveness of Warfarin therapy. It measures the clotting tendency of the patient's blood in relation to a standard measurement. The INR target range for patients on Warfarin therapy varies depending on the reason for treatment, but typically falls between 2.0 to 3.0.

Correct Answer: A

Rationale: A. Do not chew or crush extended-release forms of medication. - This instruction is important to ensure the medication is delivered in a controlled manner over an extended period.

Correct Answer: C

Rationale: Senna is a natural laxative commonly used to relieve constipation. Its primary mechanism of action is to stimulate the muscles in the intestines, leading to increased contractions and bowel movements. The evaluation of medication effectiveness for senna would typically focus on its ability to promote bowel movements and alleviate constipation. This would manifest as patients experiencing solid, formed bowel movements after taking senna. The options of decreased GI pain and irritation, healing of ulcers, and prevention of nausea and vomiting are not the primary expected outcomes when evaluating the effectiveness of senna as a medication for constipation.

Correct Answer: D

Rationale: When giving the drug Phenytoin, monitoring urinary pH is important because Phenytoin is known to be excreted by the kidneys. Changes in urinary pH can affect the concentration of Phenytoin in the body. Alkaline urine can increase the excretion of Phenytoin, potentially leading to subtherapeutic levels, while acidic urine can decrease excretion, potentially leading to toxic levels of the drug. Therefore, monitoring urinary pH helps ensure that Phenytoin levels are within the therapeutic range, minimizing the risk of either subtherapeutic or toxic effects. Monitoring for signs of toxicity, such as ataxia, nystagmus, and confusion, is also essential when administering Phenytoin.

Correct Answer: B

Rationale: 1. INR (International Normalized Ratio): INR is the primary test used to monitor the effectiveness of Warfarin therapy. It measures the clotting tendency of the patient's blood in relation to a standard measurement. The INR target range for patients on Warfarin therapy varies depending on the reason for treatment, but typically falls between 2.0 to 3.0.

Correct Answer: D

Rationale: A concentrated solution of sugar in water is known as a syrup. Syrup is commonly used in cooking and baking to add sweetness and moisture to various dishes. It is created by dissolving sugar in water over heat until a thick, sweet liquid is formed. Syrups are often used in beverages, desserts, and even as a sweetener for certain medications.

Correct Answer: D

Rationale: Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its potential to cause bone marrow depression. Bone marrow depression is a serious side effect that can lead to decreased production of blood cells, including white blood cells, red blood cells, and platelets. This can result in an increased risk of infections, anemia, and bleeding disorders. Therefore, phenylbutazone should be used cautiously and under close monitoring to avoid this complication. Aspirin, Colchicine, Ibuprofen, and Acetaminophen are not typically associated with causing bone marrow depression as a side effect.

Correct Answer: B

Rationale: "Analgesic, Antipyretic" describes the pharmacologic class of the drug, indicating that it has pain-relieving (analgesic) and fever-reducing (antipyretic) properties. Pharmacologic class refers to the category or group of medications that have similar pharmacological effects or act on the body in a similar way. In this case, the drug is categorized as an analgesic and antipyretic, which defines its primary therapeutic actions.

Correct Answer: C

Rationale: Acetaminophen is a commonly used analgesic and antipyretic, but excessive doses can lead to severe liver damage. The maximum recommended daily dose for adults is 4 grams (4000 mg). Exceeding this limit increases the risk of hepatotoxicity, which can be life-threatening. Nurses should educate patients about the importance of adhering to the recommended dosage and checking the acetaminophen content in over-the-counter medications to avoid accidental overdose. This teaching is critical for patient safety and preventing adverse outcomes.