ATI RN
Virtual ATI Pharmacology Pre Assessment Questions
Question 1 of 5
Two tests should be monitored for a patient currently on Warfarin. What are those two tests? Select ALL that apply.
Correct Answer: A
Rationale: When a patient is on Warfarin therapy, the two primary tests that need to be monitored are the Prothrombin Time (PT) and the International Normalized Ratio (INR). Warfarin works by inhibiting the activity of Vitamin K-dependent clotting factors, and both PT and INR are measures of the extrinsic pathway of coagulation, which is primarily affected by Warfarin. PT measures the time it takes for blood to clot, while INR is a standardized calculation based on the PT value to monitor the effectiveness and safety of Warfarin therapy. Monitoring these tests helps ensure that the patient's blood is not too thick (increased risk of clotting) or too thin (increased risk of bleeding) while on Warfarin.
Question 2 of 5
An older adult patient with a hip fracture became unresponsive 20 minutes after receiving morphine 3 mg intravenously. Which actions would the nurse take?
Correct Answer: C
Rationale: The patient's unresponsiveness after receiving morphine is likely due to opioid-induced respiratory depression, a potentially life-threatening side effect. The nurse should first assess the patient's airway, breathing, and circulation (ABCs) and call for additional assistance. Supporting breathing with a bag-valve-mask device is critical to ensure adequate oxygenation. Naloxone, an opioid antagonist, should be prepared to reverse the effects of morphine. Flumazenil (A) is used for benzodiazepine overdose, not opioids. Reporting a stroke (B) is incorrect because the symptoms are consistent with opioid toxicity, not a stroke. Explaining unresponsiveness as a desired outcome (D) is inappropriate and dangerous.
Question 3 of 5
What drugs interact with tetracycline? (select all that apply)
Correct Answer: B
Rationale: - Antacids can reduce the absorption of tetracycline when taken together. It is recommended to separate the administration of tetracycline and antacids by at least 2-3 hours to minimize this interaction.
Question 4 of 5
The patient is prescribed an ACE inhibitor. What primary mechanism of ACE inhibitors will the nurse understand as the therapeutic action?
Correct Answer: C
Rationale: ACE inhibitors work by inhibiting the enzyme angiotensin-converting enzyme (ACE) in the renin-angiotensin-aldosterone system (RAAS). By inhibiting ACE, the conversion of angiotensin I to angiotensin II is blocked. Angiotensin II is a potent vasoconstrictor and also stimulates the release of aldosterone from the adrenal glands. Aldosterone is a hormone that acts on the kidneys to increase reabsorption of sodium and water, leading to increased blood volume and pressure. By inhibiting aldosterone secretion, ACE inhibitors reduce blood volume and lower blood pressure, making them effective in treating hypertension and heart failure.
Question 5 of 5
A patient is taking aspirin for arthritis. Which adverse reaction should the nurse teach the patient to report to the health care provider?
Correct Answer: A
Rationale: Tinnitus, or ringing in the ears, is a classic sign of aspirin toxicity, also known as salicylism. Aspirin can cause ototoxicity at high doses, leading to hearing disturbances. Patients taking aspirin for arthritis are often on long-term therapy, which increases the risk of toxicity. Seizures, sinusitis, and palpitations are not typically associated with aspirin use. Therefore, nurses should educate patients to report tinnitus immediately, as it may indicate the need for dose adjustment or discontinuation of the medication to prevent further complications.