ATI RN
Principles of Pharmacology Quizlet Questions
Question 1 of 5
Two different pain meds are given together for pain relief. The drug-drug interaction is:
Correct Answer: A
Rationale: The correct answer is A: Synergistic. When two drugs have a synergistic interaction, they work together to produce a stronger effect than if used alone. In the case of pain meds, combining two drugs that have a synergistic interaction can lead to enhanced pain relief. This occurs because the drugs act on different pathways to produce a more effective outcome. Choices B, C, and D are incorrect: B: Antagonistic - This would mean the drugs work against each other, reducing the overall effect. C: Potentiative - This term implies that one drug enhances the effect of the other, but synergistic interaction implies a stronger combined effect. D: Additive - While this term suggests the drugs work together, it does not capture the idea of a synergistic interaction where the combined effect is greater than the sum of individual effects.
Question 2 of 5
Instructions to a client regarding self-administration of oral enteric-coated tablets should include which of the following statements?
Correct Answer: D
Rationale: The correct answer is D because enteric-coated tablets are designed to bypass the stomach and dissolve in the intestines for optimal absorption. Taking them with at least 8 ounces of fluid helps ensure the tablet reaches the intestines intact. Choice A is incorrect as it is not necessary to avoid all other oral medicines. Choice B is incorrect as dissolving an enteric-coated tablet can affect its effectiveness. Choice C is incorrect because crushing the tablet can also interfere with its intended delayed release mechanism.
Question 3 of 5
Which of the following variables is a factor in drug absorption?
Correct Answer: B
Rationale: The correct answer is B: A rich blood supply to the area of absorption leads to better absorption. A rich blood supply enhances drug absorption by allowing for faster diffusion of the drug into the bloodstream. This is because a greater blood flow increases the concentration gradient, facilitating quicker absorption. Explanation for why the other choices are incorrect: A: The statement that the smaller the surface area for absorption, the more rapidly the drug is absorbed is incorrect. Larger surface area typically leads to faster absorption due to increased contact with absorbing surfaces. C: The statement that the less soluble the drug, the more easily it is absorbed is incorrect. Solubility affects dissolution, not absorption. D: The statement that ionized drugs are easily absorbed across the cell membrane is incorrect. Ionized drugs have lower permeability across cell membranes compared to non-ionized drugs.
Question 4 of 5
Therapeutic drug levels are drawn when a drug reaches steady state. Drugs reach steady state:
Correct Answer: B
Rationale: The correct answer is B: After four to five half-lives. Steady state is achieved when the rate of drug intake equals the rate of drug elimination, typically after 4-5 half-lives. This ensures a consistent drug level in the body. Choice A is too soon for steady state. Choice C focuses on the patient's perception, not drug kinetics. Choice D is too specific and not a general rule for all drugs.
Question 5 of 5
The nurse is developing goals in collaboration with a patient. Which is the best goal statement?
Correct Answer: C
Rationale: The correct answer is C because it is specific, measurable, achievable, relevant, and time-bound (SMART). It clearly states the goal of independently self-administering the prescribed dose of albuterol by the end of the second teaching session. This goal is clear and concrete, allowing for easy evaluation of progress. Choice A is not the best because it lacks specificity regarding independence. Choice B lacks the clarity of when the goal should be achieved. Choice D is irrelevant to the specific task of self-administering albuterol. In summary, choice C is the best goal statement as it meets the criteria of a well-defined and achievable goal in collaboration with the patient.