Questions 9

ATI RN

ATI RN Test Bank

Mastering Microbiology Test Bank Questions

Question 1 of 5

Tuberculosis can be treated by means of combined chemotherapy that includes substances with different mechanisms of action. What antituberculous medication inhibits transcription of RNA into DNA in mycobacteria?

Correct Answer: A

Rationale: Rifampicin is the correct answer because it inhibits RNA transcription in mycobacteria by binding to the bacterial RNA polymerase. This prevents the synthesis of RNA, leading to the inhibition of protein production essential for bacterial growth. Isoniazid inhibits mycolic acid synthesis, Streptomycin inhibits protein synthesis, and Ethionamide disrupts mycolic acid synthesis. These mechanisms are different from inhibiting RNA transcription, making them incorrect choices.

Question 2 of 5

A 34-year-old male visited Tajikistan. After return, he complains of fever up to 40oC which occurs every second day and is accompanied by chills, sweating. Hepatosplenomegaly is present. Blood test results: RBC- 3x1012/l, b- 80 g/l, WBC- 4x109/l, eosinophils - 1%, stab neutrophils - 5%, segmented neutrophils - 60%, lymphocytes - 24%, monocytes - 10%, ESR - 25 mm/h. What is the provisional diagnosis?

Correct Answer: A

Rationale: The correct answer is A: Malaria. The patient's travel history to an endemic area like Tajikistan, along with symptoms of fever with chills, sweating, and hepatosplenomegaly, are classic for malaria. The blood test results show anemia (low RBC and hemoglobin levels), which can occur in malaria due to hemolysis. The presence of eosinophils and lymphocytes are not typical for malaria, but the overall clinical picture fits. Infectious mononucleosis (choice B) typically presents with sore throat, lymphadenopathy, and atypical lymphocytosis, which are not seen in this case. Sepsis (choice C) is characterized by systemic inflammatory response syndrome and organ dysfunction due to infection, which does not align with the symptoms and findings in the case. Typhoid fever (choice D) usually presents with gradual onset of sustained fever, abdominal pain, headache, and constipation, which are not present in this patient

Question 3 of 5

Microscopy of a wound abscess revealed Gram-negative rods producing blue-green pigment with a distinctive odor of jasmine. What is the likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is known for producing a blue-green pigment called pyocyanin, which gives the characteristic color seen in the wound abscess. The distinctive odor of jasmine is also a key feature of Pseudomonas aeruginosa. Proteus vulgaris (B) and Klebsiella pneumoniae (D) do not produce blue-green pigment or have a jasmine-like odor. Escherichia coli (C) typically does not produce blue-green pigment or have a jasmine-like odor.

Question 4 of 5

Which of the following bacteria are unable to synthesize ATP?

Correct Answer: A

Rationale: The correct answer is A: Chlamydia. Chlamydia lacks the essential enzymes for ATP synthesis and relies on host cell ATP. Enterococci, Rickettsia, and Staphylococci possess the necessary enzymes for ATP synthesis through cellular respiration. Chlamydia's inability to synthesize ATP makes it dependent on the host cell for energy production, distinguishing it from the other bacteria listed.

Question 5 of 5

Which bacteria produces an enterotoxin that causes diarrhea?

Correct Answer: A

Rationale: The correct answer is A: Vibrio cholerae. This bacterium produces the cholera toxin, an enterotoxin that causes profuse watery diarrhea by disrupting the normal function of the intestines. Vibrio cholerae is specifically known for causing cholera, a severe diarrheal disease. Clostridium botulinum (B) produces botulinum toxin, causing botulism (paralysis, not diarrhea). Escherichia coli (C) can produce enterotoxins, but the question specifies a specific enterotoxin causing diarrhea, which is not a characteristic of all strains of E. coli. Streptococcus pneumoniae (D) is a common cause of respiratory infections but does not produce an enterotoxin causing diarrhea.

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