Transfusion of fresh frozen plasma (FFP) is efficacious for the treatment of deficiency of all the following coagulation factors EXCEPT

Correct Answer: D

Rationale: FFP provides factors V (A), X (B), XI (C), and protein C (E), but factor XIII (D) has low levels in FFP, requiring cryoprecipitate or concentrates for deficiency.

Correct Answer: B

Rationale: Factor XIII has a 5-7 day half-life (A), is screened by clot solubility (C), assayed specifically (D), and needs 2-3% for hemostasis (E). PT, PTT, and TT (B) are normal in its deficiency, as it affects clot stability, not formation.

Correct Answer: C

Rationale: Factor V Leiden is common (A), worse in homozygotes (B), increases venous thrombosis with OCPs (D), and causes abortions (E). Arterial thrombosis (C) is not significantly increased, making it false.

Correct Answer: C

Rationale: Neonatal bruising, melena, and prolonged PT/PTT with normal platelets and fibrinogen suggest vitamin K deficiency (C), common in newborns without prophylaxis. DIC (A) lowers fibrinogen, hemophilia (B) is sex-linked, heparin (D) isn’t transferred via breast milk, and lupus anticoagulants (E) don’t cause bleeding.

Correct Answer: A

Rationale: Acute ITP (A) typically resolves within months, unlike chronic conditions SLE (B), HIV (C), type 2B vWD (D), and WAS (E), which cause prolonged thrombocytopenia.