To prevent inadvertent complement activation, eight inhibitors exist. Which of the following is an inhibitor preventing activation of C2 and C4, and prevents C3 activation by the alternative pathway?

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Pediatric Immunization NCLEX Questions Questions

Question 1 of 5

To prevent inadvertent complement activation, eight inhibitors exist. Which of the following is an inhibitor preventing activation of C2 and C4, and prevents C3 activation by the alternative pathway?

Correct Answer: A

Rationale: C1 inhibitor regulates C2/C4 in the classical/lectin pathways and indirectly affects C3.

Question 2 of 5

Enhance diapedesis and stimulate TH2 responses

Correct Answer: C

Rationale: IL-4, a cytokine, promotes diapedesis (leukocyte migration) and drives TH2 responses critical for parasitic immunity.

Question 3 of 5

Degrade host cell proteins, activate caspase enzyme system

Correct Answer: B

Rationale: Granzymes enter target cells via perforin pores, degrading proteins and activating caspases for apoptosis.

Question 4 of 5

Immunostimulatory complexes (ISCOMS) can be used for mucosal vaccines and induce widespread mucosal immunity in the gut and respiratory tract. They are the one way that response can be promoted.

Correct Answer: C

Rationale: ISCOMS enhance cytotoxic T cell responses, critical for mucosal immunity.

Question 5 of 5

A patient presents in the winter months with swollen lips. The patient says they forgot their lip balm. Uncontrolled activation of the classical complement pathway is responsible for the swelling. Records show the patient has a C1 inh deficiency. Which of the following does this patient have?

Correct Answer: C

Rationale: Hereditary angioedema results from C1 inhibitor deficiency, causing uncontrolled complement activation and swelling.

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