ATI RN
Chemotherapy drugs Questions
Question 1 of 5
To be effective in ulcerative colitis, 5-aminosalicylic acid has to be given as
Correct Answer: D
Rationale: 5-ASA is effective in ulcerative colitis via all these delivery methods, targeting the colon specifically.
Question 2 of 5
Indicate the condition in which neither trimethoprim nor sulfamethoxazole alone are effective, but their combination cotrimoxazole is
Correct Answer: C
Rationale: Cotrimoxazole is uniquely effective against Pneumocystis jirovecii pneumonia due to synergistic folate pathway inhibition.
Question 3 of 5
Indicate the drug which attain therapeutic antibacterial concentration in the urinary tract but not in other tissues
Correct Answer: C
Rationale: Nitrofurantoin concentrates in urine, achieving therapeutic levels there but not in other tissues.
Question 4 of 5
The intermittently multiplying (spurter) tubercle bacilli present within caseous material having low oxygen tension are most susceptible to
Correct Answer: B
Rationale: Rifampin is most effective against intermittently multiplying TB bacilli in low-oxygen environments like caseous lesions.
Question 5 of 5
Ethambutol is not used in children below 6 years of age because
Correct Answer: C
Rationale: Ethambutol’s visual toxicity (optic neuritis) is hard to detect in young children, who cannot reliably report symptoms.