Tick the stimulant of bile production of vegetable origin:

Correct Answer: D

Rationale: Step-by-step rationale: 1. Cholosas is a bile stimulant of vegetable origin, containing bile salts. 2. Bile salts in Cholosas promote the production of bile in the liver, aiding in digestion. 3. Oxaphenamide and Papaverine are not bile stimulants. 4. Cholenzyme is an enzyme supplement, not a bile stimulant. In summary, Cholosas is the correct answer as it directly stimulates bile production, while the other choices are not related to bile production.

Correct Answer: A

Rationale: Rationale: A: Incorrect. Calcium channel blockers do not release nitric oxide. They mainly block calcium entry into cells. B: Correct. L-type calcium channels are the main target of calcium channel blockers. C: Correct. Calcium channel blockers decrease oxygen demand and increase oxygen delivery in angina. D: Correct. Calcium channel blockers reduce calcium entry, leading to relaxation in smooth muscle and decreased contractility in cardiac muscle. Therefore, choice A is incorrect because calcium channel blockers do not release nitric oxide.

Correct Answer: B

Rationale: Step-by-step rationale: 1. Digoxin is a positive inotropic drug of glycoside structure. 2. Digoxin works by inhibiting the sodium-potassium pump, leading to increased intracellular calcium levels, enhancing myocardial contractility. 3. Dopamine is a catecholamine used for its positive inotropic effects but does not have a glycoside structure. 4. Dobutamine is a synthetic catecholamine with positive inotropic effects but lacks a glycoside structure. 5. Adrenaline is a catecholamine with positive inotropic effects, but it is not a glycoside structure. Summary: Digoxin is the correct answer because it has a glycoside structure and exerts positive inotropic effects by increasing intracellular calcium levels. Dopamine, dobutamine, and adrenaline are not glycoside drugs and work through different mechanisms.

Correct Answer: D

Rationale: The correct answer is D: For treatment of simple obesity. Thyroid hormones are not indicated for the treatment of simple obesity as they do not directly affect weight loss. A: Cretinism - Thyroid hormones are indicated for the treatment of cretinism, a condition caused by thyroid hormone deficiency in infancy. B: Myxoedema - Thyroid hormones are indicated for the treatment of myxoedema, a severe form of hypothyroidism in adults. C: Hashimoto's disease - Thyroid hormones are indicated for the treatment of Hashimoto's disease, an autoimmune condition that leads to hypothyroidism. In summary, thyroid hormones are indicated for conditions related to thyroid hormone deficiencies and dysfunctions, but not for the treatment of simple obesity.

Correct Answer: A

Rationale: The correct answer is A: Antiprogestin. Mifepristone is a synthetic steroid that acts as an antiprogestin by competitively binding to progesterone receptors, blocking the effects of progesterone. It is commonly used for medical abortion and in the treatment of conditions like Cushing's syndrome. Explanation for incorrect choices: B: Antiandrogen - Mifepristone does have some antiandrogenic properties, but its primary mechanism of action is as an antiprogestin. C: Antiestrogen - Mifepristone is not an antiestrogen; it does not block estrogen receptors. D: Androgen - Mifepristone is not an androgen; it is a synthetic steroid with antiprogestational activity.