Tick the estrogen inhibitor:

Correct Answer: D

Rationale: The correct answer is D: Anastrozole. Anastrozole is an aromatase inhibitor that works by blocking the enzyme aromatase, which is responsible for converting androgens into estrogen. By inhibiting estrogen production, Anastrozole effectively reduces estrogen levels in the body. Leuprolide (A) is a gonadotropin-releasing hormone agonist that suppresses estrogen production indirectly. Tamoxifen (B) is a selective estrogen receptor modulator that blocks estrogen receptors. Flutamide (C) is an antiandrogen that blocks the effects of androgens, not estrogen.

Correct Answer: C

Rationale: The correct answer is C because cholestyramine can bind to propranolol in the gut, preventing its absorption and leading to an increase in oral bioavailability. This occurs due to the cholestyramine-propranolol complex being excreted in the feces, reducing the amount of propranolol available for systemic circulation. Choice A is incorrect because propranolol clearance would decrease, not increase, as less drug is absorbed and more is excreted in the feces. Choice B is incorrect as cholestyramine does not directly affect the clearance of hydrochlorothiazide. Choice D is incorrect as there is a clear pharmacokinetic interaction between cholestyramine and propranolol.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.