Tick the drug used for trichomoniasis treatment:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Metronidazole is the drug of choice for trichomoniasis due to its efficacy against the parasite. 2. Metronidazole works by disrupting the DNA structure of the parasite, leading to its death. 3. Suramin is used for African sleeping sickness, not trichomoniasis. 4. Pyrimethamine is used for malaria, not trichomoniasis. 5. Tetracycline is used for bacterial infections, not trichomoniasis. Summary: Metronidazole is the correct choice for trichomoniasis treatment due to its specific mechanism of action against the parasite. Suramin, pyrimethamine, and tetracycline are used for different infections and are not effective for trichomoniasis.

Correct Answer: B

Rationale: The correct answer is B: Amiodarone-induced increase in digoxin plasma levels. Amiodarone inhibits digoxin clearance, leading to increased digoxin levels, which can cause symptoms such as nausea, vomiting, and arrhythmias. The other choices are less likely as captopril is not typically associated with hyperkalemia, amiodarone does not commonly affect atrioventricular conduction, and furosemide-induced diuresis would not explain the symptoms mentioned.

Correct Answer: A

Rationale: The correct answer is A: Inhibition of carbonic acid dehydration in the tubular lumen. Acetazolamide is a carbonic anhydrase inhibitor that works in the proximal convoluted tubule of the kidney to reduce bicarbonate reabsorption. By inhibiting carbonic anhydrase, it prevents the conversion of carbonic acid to bicarbonate and H+, leading to increased excretion of bicarbonate in the urine. This results in a systemic metabolic acidosis and a diuretic effect. Choices B, C, and D are incorrect because acetazolamide does not directly stimulate bicarbonate reabsorption in the proximal tubule, inhibit Na+ reabsorption in the early distal tubule, or stimulate H+ reabsorption in the proximal tubule. The primary mechanism of action of acetazolamide is through carbonic anhydrase inhibition, leading to its therapeutic effects.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.