Tick the drug used for trichomoniasis treatment:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Metronidazole is the drug of choice for trichomoniasis due to its efficacy against the parasite. 2. Metronidazole works by disrupting the DNA structure of the parasite, leading to its death. 3. Suramin is used for African sleeping sickness, not trichomoniasis. 4. Pyrimethamine is used for malaria, not trichomoniasis. 5. Tetracycline is used for bacterial infections, not trichomoniasis. Summary: Metronidazole is the correct choice for trichomoniasis treatment due to its specific mechanism of action against the parasite. Suramin, pyrimethamine, and tetracycline are used for different infections and are not effective for trichomoniasis.

Correct Answer: B

Rationale: The correct answer is B: Amiodarone-induced increase in digoxin plasma levels. Amiodarone inhibits digoxin clearance, leading to increased digoxin levels, which can cause symptoms such as nausea, vomiting, and arrhythmias. The other choices are less likely as captopril is not typically associated with hyperkalemia, amiodarone does not commonly affect atrioventricular conduction, and furosemide-induced diuresis would not explain the symptoms mentioned.

Correct Answer: A

Rationale: The correct answer is A: Inhibition of carbonic acid dehydration in the tubular lumen. Acetazolamide is a carbonic anhydrase inhibitor that works in the proximal convoluted tubule of the kidney to reduce bicarbonate reabsorption. By inhibiting carbonic anhydrase, it prevents the conversion of carbonic acid to bicarbonate and H+, leading to increased excretion of bicarbonate in the urine. This results in a systemic metabolic acidosis and a diuretic effect. Choices B, C, and D are incorrect because acetazolamide does not directly stimulate bicarbonate reabsorption in the proximal tubule, inhibit Na+ reabsorption in the early distal tubule, or stimulate H+ reabsorption in the proximal tubule. The primary mechanism of action of acetazolamide is through carbonic anhydrase inhibition, leading to its therapeutic effects.

Correct Answer: B

Rationale: In this question, the correct answer is B) Digoxin. Digoxin is classified chemically as a glycoside because it contains a sugar molecule attached to a non-sugar molecule. This chemical structure is characteristic of glycosides. Digoxin is commonly used in the treatment of heart failure and certain arrhythmias. A) Nifedipine is a calcium channel blocker used to treat hypertension and angina. It does not belong to the glycoside class of drugs. C) Flecainide is a class Ic antiarrhythmic agent used to treat certain types of arrhythmias. It is not a glycoside. D) Cholestyramine is a bile acid sequestrant used to lower cholesterol levels. It is not classified as a glycoside. Understanding the classification of drugs based on their chemical structure is essential for healthcare professionals to accurately prescribe and administer medications. Knowing that digoxin is a glycoside helps healthcare providers understand its mechanism of action and potential side effects. This knowledge is crucial for safe and effective patient care in the management of cardiovascular conditions.

Correct Answer: C

Rationale: In this question from the FHEA Drugs That Affect the Cardiovascular System Quizlet, the correct answer is C) Intramuscular. Glyceryl trinitrate, commonly known as nitroglycerin, is a medication used to treat angina and heart failure by dilating blood vessels to increase blood flow. The correct route of administration for glyceryl trinitrate is typically sublingual or transdermal. Sublingual administration allows for rapid absorption through the oral mucosa, leading to quicker onset of action in case of angina attacks. Intramuscular administration would result in slower absorption and potentially inconsistent efficacy in treating acute symptoms. Oral administration is not ideal for glyceryl trinitrate due to extensive first-pass metabolism in the liver, reducing its bioavailability. Intravenous administration of glyceryl trinitrate is reserved for severe cases in a clinical setting where immediate and precise dosing is required. In an educational context, understanding the appropriate route of administration for medications like glyceryl trinitrate is crucial for healthcare professionals to ensure optimal patient outcomes and safety. It emphasizes the importance of pharmacokinetics, drug delivery mechanisms, and the impact of route selection on drug effectiveness in cardiovascular care.