Tick the drug belonging to non-selective beta2-adrenomimics:

Questions 52

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Cardiovascular System Drugs Classification Questions

Question 1 of 5

Tick the drug belonging to non-selective beta2-adrenomimics:

Correct Answer: B

Rationale: The correct answer is B: Isoprenaline. Isoprenaline is a non-selective beta2-adrenomimic because it stimulates both beta1 and beta2 adrenergic receptors. This leads to effects on both the heart and lungs. Salbutamol, Salmeterol, and Terbutaline are selective beta2-adrenomimics, meaning they primarily target beta2 receptors in the lungs, resulting in bronchodilation without significant effects on the heart. Therefore, they do not belong to the category of non-selective beta2-adrenomimics like Isoprenaline.

Question 2 of 5

Tolerance to this inotropic drug develops after a few days:

Correct Answer: C

Rationale: Rationale: 1. Dobutamine is a beta-1 adrenergic receptor agonist used as an inotropic drug. 2. Continuous use of dobutamine leads to receptor desensitization, causing tolerance. 3. Tolerance develops within a few days due to downregulation of beta-1 receptors. 4. Amrinone and amiodarone are not inotropic drugs and do not cause tolerance. 5. Adenosine is not an inotropic drug and has a rapid onset and short duration of action.

Question 3 of 5

The following agents are cardioselective beta1-adrenoceptor-blocking drugs labeled for use in angina, EXCEPT:

Correct Answer: D

Rationale: The correct answer is D: Propranolol. Propranolol is a non-selective beta-blocker, affecting both beta1 and beta2 receptors. In contrast, choices A, B, and C are cardioselective beta1-adrenoceptor-blocking drugs. Metoprolol, Talinolol, and Atenolol specifically target beta1 receptors in the heart, making them suitable for angina treatment. Propranolol, being non-selective, may lead to unwanted side effects related to beta2 receptor blockade, such as bronchoconstriction and peripheral vasoconstriction. Therefore, for angina patients, cardioselective beta1 blockers are preferred to minimize potential adverse effects.

Question 4 of 5

Tick the group of drugs for chronic hypotension treatment:

Correct Answer: B

Rationale: The correct answer is B: Vasoconstrictors. Vasoconstrictors are used to increase blood pressure in chronic hypotension by constricting blood vessels, thus raising blood pressure. Positive inotropic drugs (A) increase the strength of the heart's contractions, which is not the primary concern in hypotension. Plasmoexpanders (C) are used to increase blood volume, not necessarily blood pressure. Analeptics and tonics (D) are more commonly used for conditions like fatigue or depression, not specifically for chronic hypotension.

Question 5 of 5

Radioiodines (I131 and I132) is suitable for:

Correct Answer: A

Rationale: The correct answer is A: Elderly patients (over 45 years). Radioiodines are suitable for elderly patients due to their slower metabolism, which allows for better uptake and retention of the radioiodine in the thyroid gland. This results in more effective treatment of conditions like hyperthyroidism or thyroid cancer. Pregnant women, nursing mothers, and younger patients should avoid radioiodine therapy due to potential risks to the fetus, infant, and developing thyroid gland, respectively. Overall, the slower metabolism in elderly patients makes them the most suitable candidates for radioiodine therapy.

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