ATI RN
Advanced Pharmacology Across the Lifespan Questions
Question 1 of 5
Tick the drug, a derivative of pyrophosphate:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
Action mechanism of alkylating agents is:
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Tick the estrogen inhibitor:
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following is not a good prognostic factor in patient with acute lymphoblastic leukemia?
Correct Answer: A
Rationale: In acute lymphoblastic leukemia (ALL), good prognostic factors include female gender (B), hyperploidy (C, >50 chromosomes), and age 4-10 years (D). Mature B-cell immunophenotype (A) is associated with Burkitt leukemia, a subtype of ALL with poorer prognosis due to aggressive behavior, unlike precursor B- or T-cell ALL. Expression of ZAP-70 (E) is more relevant to CLL, not ALL, but A is the clear poor prognostic factor here.
Question 5 of 5
A patient who is infected with hookworms produces signs and symptoms of anemia. Which of the following can be seen in the peripheral blood smear of the patient?
Correct Answer: B
Rationale: Hookworm infection causes iron deficiency anemia due to chronic blood loss. Peripheral blood smears may show microcytic, hypochromic RBCs and occasionally basophilic stippling (B), which can occur in severe anemia or lead poisoning (less common here but possible). Howell-Jolly bodies (A) indicate asplenia, target cells (C) thalassemia or liver disease, spherocytes (D) hereditary spherocytosis, and Pappenheimer bodies (E) sideroblastic anemia—none are specific to hookworm-induced iron deficiency, but B is most plausible.