Tick the antitussive agent with a peripheral effect:

Correct Answer: C

Rationale: Step 1: Identify the antitussive agents that have a peripheral effect. Step 2: Understand that antitussive agents with a peripheral effect act outside the central nervous system. Step 3: Recognize that Libexine is the only antitussive agent among the choices that exerts its effect peripherally. Step 4: Codeine and Tusuprex primarily act centrally, not peripherally. Step 5: Glaucine hydrochloride is a smooth muscle relaxant and not typically classified as an antitussive agent with a peripheral effect.

Correct Answer: D

Rationale: The correct answer is D because glycosides intoxication can lead to a range of cardiac manifestations, including atrioventricular junctional rhythm, second-degree atrioventricular blockade, and ventricular tachycardia. These effects are due to the toxic effects of glycosides on the heart's electrical conduction system. Atrioventricular junctional rhythm occurs when the impulse originates in the atrioventricular node, leading to a slower heart rate. Second-degree atrioventricular blockade involves a delay or interruption in the electrical signals between the atria and ventricles. Ventricular tachycardia is a rapid heart rhythm originating in the ventricles. Therefore, all of the above options are correct manifestations of glycosides intoxication.

Correct Answer: A

Rationale: Rationale: A: Incorrect. Calcium channel blockers do not release nitric oxide. They mainly block calcium entry into cells. B: Correct. L-type calcium channels are the main target of calcium channel blockers. C: Correct. Calcium channel blockers decrease oxygen demand and increase oxygen delivery in angina. D: Correct. Calcium channel blockers reduce calcium entry, leading to relaxation in smooth muscle and decreased contractility in cardiac muscle. Therefore, choice A is incorrect because calcium channel blockers do not release nitric oxide.

Correct Answer: B

Rationale: Step-by-step rationale: 1. Digoxin is a positive inotropic drug of glycoside structure. 2. Digoxin works by inhibiting the sodium-potassium pump, leading to increased intracellular calcium levels, enhancing myocardial contractility. 3. Dopamine is a catecholamine used for its positive inotropic effects but does not have a glycoside structure. 4. Dobutamine is a synthetic catecholamine with positive inotropic effects but lacks a glycoside structure. 5. Adrenaline is a catecholamine with positive inotropic effects, but it is not a glycoside structure. Summary: Digoxin is the correct answer because it has a glycoside structure and exerts positive inotropic effects by increasing intracellular calcium levels. Dopamine, dobutamine, and adrenaline are not glycoside drugs and work through different mechanisms.

Correct Answer: D

Rationale: The correct answer is D: For treatment of simple obesity. Thyroid hormones are not indicated for the treatment of simple obesity as they do not directly affect weight loss. A: Cretinism - Thyroid hormones are indicated for the treatment of cretinism, a condition caused by thyroid hormone deficiency in infancy. B: Myxoedema - Thyroid hormones are indicated for the treatment of myxoedema, a severe form of hypothyroidism in adults. C: Hashimoto's disease - Thyroid hormones are indicated for the treatment of Hashimoto's disease, an autoimmune condition that leads to hypothyroidism. In summary, thyroid hormones are indicated for conditions related to thyroid hormone deficiencies and dysfunctions, but not for the treatment of simple obesity.