Tick the action mechanism of anticancer drugs belonging to plant alkaloids:

Correct Answer: C

Rationale: The correct answer is C: Mitotic arrest at metaphase. Plant alkaloids like vinca alkaloids and taxanes disrupt microtubule function, leading to mitotic arrest at metaphase. This prevents cell division and ultimately inhibits cancer cell growth. Option A is incorrect because plant alkaloids do not directly inhibit DNA-dependent RNA synthesis. Option B is incorrect as cross-linking of DNA is not a mechanism of action for plant alkaloids. Option D is incorrect as plant alkaloids do not target aromatases. In summary, the correct mechanism for plant alkaloids is disrupting microtubule function, leading to mitotic arrest at metaphase.

Correct Answer: A

Rationale: The correct answer is A: Hydrochlorothiazide. This diuretic is appropriate for a patient with hypertension due to its ability to reduce blood volume and lower blood pressure. It is often recommended as a first-line treatment for essential hypertension. Propranolol (B) is a beta-blocker that may not be as effective as a diuretic in this case. Captopril (C) is an ACE inhibitor that may be used as an alternative, but not as the most appropriate choice. Clonidine (D) is a centrally acting alpha-2 agonist and typically considered a second-line treatment option.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.