ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
Ticarcillin is relatively unique among all the penicillins because it poses a greater risk of a relatively unique side effect or adverse response. Which of the following best summarizes what that unique unwanted effect is?
Correct Answer: D
Rationale: Ticarcillin’s high sodium content can cause hypertension, hypervolemia, and bleeding tendencies.
Question 2 of 5
A 50-year-old man with Type 2 diabetes develops an otitis from which Pseudomonas organisms are cultured. Topical therapy with polymyxin B is effective. Which of the following best explains the drug's mechanism of action?
Correct Answer: A
Rationale: Polymyxin B disrupts bacterial membrane permeability, targeting gram-negative bacteria like Pseudomonas.
Question 3 of 5
A 39-year-old woman with a history of recurrent urinary tract infections develops a new infection. Culture of a urine sample indicated that the offending organism is Escherichia coli. She receives therapeutic doses of ciprofloxacin. Symptoms disappear as the offending bacteria are destroyed. Which of the following is the main bacterial process or enzyme that was inhibited by levofloxacin?
Correct Answer: C
Rationale: Ciprofloxacin (not levofloxacin as stated, likely a typo) inhibits DNA gyrase, stopping E. coli replication.
Question 4 of 5
All the following drugs are oral anticoagulants EXCEPT:
Correct Answer: D
Rationale: Dabigatran, rivaroxaban, and warfarin are oral anticoagulants, while bivalirudin is administered intravenously, typically in acute settings like percutaneous coronary intervention.
Question 5 of 5
The following is INCORRECT about dabigatran:
Correct Answer: A
Rationale: Dabigatran has a rapid onset (~1-2 hours) but its half-life is 12-17 hours, not up to 6 days. PPIs reduce absorption, it’s safer in liver failure than warfarin, it’s dialyzable, and idarucizumab is its antidote.