ATI RN
Immune System NCLEX Questions Questions
Question 1 of 5
Thymus dependent zone of the spleen is present at:
Correct Answer: A
Rationale: Thymus-dependent zone in spleen is the periarteriolar lymphatic sheath (PALS) around the central arteriole .
Question 2 of 5
Which co-stimulatory molecule is used by APCs to activate T cells?
Correct Answer: A
Rationale: APCs use B7 to bind CD28 on T cells for co-stimulation ; CD4/CD8 (B, C) are T-cell co-receptors, CD40 is for B cells.
Question 3 of 5
Which cells are recruited to the site of infection during DTH?
Correct Answer: B
Rationale: DTH recruits macrophages and neutrophils ; T cells drive it, but B cells and NK cells are less central.
Question 4 of 5
Which of these is not a function of lymph nodes?
Correct Answer: C
Rationale: Lymph nodes house and produce lymphocytes, filter lymph , but red blood cell production occurs in bone marrow, not lymph nodes.
Question 5 of 5
Some Pattern Recognition Receptors (PRRs) recognize nucleic acids, like RNA or DNA. Since our own cells contain human RNA and DNA, the activation of innate immune pathways by these PRRs must rely on additional criteria to discriminate self from nonself. Additional criteria include everything EXCEPT:
Correct Answer: B
Rationale: PRRs distinguish self via RNA location , DNA methylation , and viral RNA structures ; adenosine presence isn't a key discriminator.