ATI RN
ATI Pharmacology Proctored Exam 2024 Quizlet Questions
Question 1 of 5
This serves as an indication of time required for a dosing regimen to achieve a steady state concentration of drug in blood
Correct Answer: B
Rationale: The half-life is the time required for the concentration of a drug in the blood to decrease by 50%. It serves as an indication of the time required for a dosing regimen to achieve a steady state concentration of the drug in the blood. Understanding the half-life of a drug is crucial for determining the dosing interval needed to maintain therapeutic levels. Long half-lives require less frequent dosing to reach steady state, while short half-lives demand more frequent dosing to achieve the desired drug concentration in the blood over time.
Question 2 of 5
A patient who is taking clopidogrel (Plavix) and aspirin is preparing for orthopedic surgery. The nurse will consult with the surgeon and provide which instruction to the patient?
Correct Answer: A
Rationale: The correct instruction for the patient taking clopidogrel (Plavix) and aspirin prior to orthopedic surgery is to continue taking aspirin and stop taking clopidogrel 2 weeks before the surgery. This recommendation is based on the pharmacokinetics of clopidogrel, which has a longer duration of action and requires a longer timeframe for platelet function to return to baseline after discontinuation. Aspirin, on the other hand, has a shorter duration of action, and its antiplatelet effects diminish more rapidly once it is stopped. By continuing aspirin and stopping clopidogrel 2 weeks before surgery, the patient can minimize the risk of excessive bleeding during the surgical procedure while still maintaining some level of antiplatelet effect to prevent thrombotic events.
Question 3 of 5
Which drug must be administered intravenously?
Correct Answer: B
Rationale: Interleukin 2 is administered intravenously because it is a protein that would be broken down in the digestive system if taken orally. Epoetin alfa, granulocyte colony–stimulating factor (G-CSF), and granulocyte-macrophage colony–stimulating factor (GM-CSF) can be administered subcutaneously. The nurse should ensure proper administration of interleukin 2 and monitor for side effects, such as capillary leak syndrome, which can cause fluid retention and hypotension.
Question 4 of 5
The school nurse prepares a program for junior high school students on sun safety. Which information will the nurse include? (Select all that apply.)
Correct Answer: B
Rationale: Sunscreen should provide protection against both UVA and UVB radiation and include SPF information (A). UVB radiation is most intense between 10 a.m. and 2 p.m. (B). An SPF of at least 15 is recommended (D). Clouds do not block all radiation, so sunscreen is still needed on cloudy days (C is incorrect).
Question 5 of 5
The nurse is reviewing factors that influence pharmacokinetics in the neonatal patient. Which factor puts the neonatal patient at risk with regard to drug therapy?
Correct Answer: A
Rationale: Neonates have an immature renal system, which affects the excretion of drugs and their metabolites. This immaturity can lead to prolonged drug half-lives and an increased risk of toxicity. While hyperperistalsis, irregular temperature regulation, and smaller circulatory capacity can influence drug therapy, the immature renal system is the most significant factor. Nurses must consider this when administering medications to neonates and adjust dosages accordingly to ensure safety and efficacy.