Correct Answer: C

Rationale: The correct answer is C: Quinine. Quinine is known for its destructive effect on erythrocytic forms of malarial plasmodia and dysenteric amoebae. It is commonly used for the treatment and prevention of diseases such as malaria, amebiasis, and interstitial disease. Quinine works by interfering with the parasite's ability to break down hemoglobin in red blood cells, ultimately leading to their destruction. Incorrect choices: A: Chingamin - Chingamin is not typically used to treat malaria, amebiasis, or interstitial disease. B: Emetine hydrochloride - Emetine hydrochloride is primarily used for treating amoebic dysentery and is not commonly used for malaria treatment. D: Erythromycin - Erythromycin is an antibiotic used to treat bacterial infections, not parasitic infections like malaria or amebiasis.

Correct Answer: A

Rationale: The correct answer is A: Escherichia coli. E. coli is a Gram-negative rod that ferments lactose, leading to red colonies on Endo agar. This bacterium is commonly found in the human gut and is known for its ability to ferment lactose. Salmonella and Shigella are also Gram-negative rods but do not ferment lactose, so they would not produce red colonies on Endo agar. Proteus is a Gram-negative rod that is not known for its lactose-fermenting ability and would not produce red colonies on Endo agar. Therefore, based on the characteristics provided, E. coli is the most likely microorganism responsible for the red colonies on Endo agar.

Correct Answer: B

Rationale: The correct answer is B: Coxiella burnetii. Q-fever is caused by the bacterium Coxiella burnetii. It is not caused by viruses like Bunyaviridae or Filoviridae. Rickettsia conorii causes Mediterranean spotted fever, not Q-fever. Coxiella burnetii is the only bacterium among the choices known to be the etiological agent of Q-fever.

Correct Answer: A

Rationale: The correct answer is A: Streptomycin. Streptomycin is an aminoglycoside antibiotic used to treat tuberculosis that can cause hearing loss as a side effect. It is known to damage the cochlear and vestibular organs in the inner ear. The other choices, B: Isoniazid, C: Rifampicin, and D: Ethionamide, are not associated with causing hearing deterioration as a side effect. Isoniazid can rarely cause peripheral neuropathy, Rifampicin can lead to hepatotoxicity, and Ethionamide may cause gastrointestinal disturbances, but none of these drugs are known to specifically cause hearing loss.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Clostridium tetani, Staphylococcus aureus, and Escherichia coli are all capable of producing exotoxins. Exotoxins are proteins released by bacteria that can cause damage to the host. Clostridium tetani produces tetanospasmin, causing tetanus. Staphylococcus aureus produces toxins like enterotoxin and toxic shock syndrome toxin-1. Escherichia coli can produce Shiga toxin and heat-labile toxin. Therefore, all three bacteria listed can produce exotoxins, making choice D the correct answer. Choices A, B, and C are incorrect as they do not encompass all the bacteria capable of producing exotoxins.