This drug has a destructive effect on erythrocytic forms of malarial plasmodia and dysenteric amoebae. It is used for treatment and prevention of such diseases as malaria, amebiasis and interstitial disease. What drug is it?

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Microbiology An Introduction 12th Edition Test Bank Questions

Question 1 of 9

This drug has a destructive effect on erythrocytic forms of malarial plasmodia and dysenteric amoebae. It is used for treatment and prevention of such diseases as malaria, amebiasis and interstitial disease. What drug is it?

Correct Answer: C

Rationale: The correct answer is C: Quinine. Quinine is known for its destructive effect on erythrocytic forms of malarial plasmodia and dysenteric amoebae. It is commonly used for the treatment and prevention of diseases such as malaria, amebiasis, and interstitial disease. Quinine works by interfering with the parasite's ability to break down hemoglobin in red blood cells, ultimately leading to their destruction. Incorrect choices: A: Chingamin - Chingamin is not typically used to treat malaria, amebiasis, or interstitial disease. B: Emetine hydrochloride - Emetine hydrochloride is primarily used for treating amoebic dysentery and is not commonly used for malaria treatment. D: Erythromycin - Erythromycin is an antibiotic used to treat bacterial infections, not parasitic infections like malaria or amebiasis.

Question 2 of 9

The eukaryotes known for the presence of a macronucleus and a micronucleus are:

Correct Answer: C

Rationale: The correct answer is C: protozoans. Protozoans are eukaryotic organisms that possess both a macronucleus, responsible for general cell functions, and a micronucleus, involved in genetic processes like reproduction. Algae (choice A) typically have a single nucleus, fungi (choice B) lack distinct macronucleus and micronucleus structures, and slime molds (choice D) do not have the same nucleus organization as protozoans. Thus, protozoans are the only group among the choices that exhibit the specific characteristics of having both a macronucleus and a micronucleus.

Question 3 of 9

In the South and Central America there can be found a species of trypanosomes that is the causative agent of Chagas disease. What animal is the infection carrier specific to this disease?

Correct Answer: A

Rationale: The correct answer is A: Triatomine bug. Triatomine bugs, also known as "kissing bugs," are the specific carrier of the trypanosomes that cause Chagas disease. These bugs transmit the parasite through their feces, which contain the infectious forms of the trypanosomes. When the bug bites a human or animal, it defecates near the bite wound, allowing the parasites to enter the bloodstream through the broken skin. Mosquitoes (B) transmit diseases like malaria and dengue fever, not Chagas disease. Tsetse flies (C) are known for transmitting African trypanosomiasis (sleeping sickness), not Chagas disease. Cockroaches (D) are not known to transmit Chagas disease.

Question 4 of 9

A patient with a productive cough and fever had a Gram-positive cocci isolated from a sputum sample. The bacteria were catalase-positive and coagulase-negative. What is the likely microorganism?

Correct Answer: A

Rationale: The correct answer is A: Staphylococcus epidermidis. 1. Gram-positive cocci suggest a staphylococcal species. 2. Catalase-positive indicates it belongs to the Staphylococcus genus. 3. Coagulase-negative rules out Staphylococcus aureus. 4. Staphylococcus epidermidis is a common cause of infections in immunocompromised patients. Summary: - B: Staphylococcus aureus is coagulase-positive. - C: Streptococcus pneumoniae is a Gram-positive diplococci. - D: Neisseria meningitidis is a Gram-negative diplococci.

Question 5 of 9

Carious cavities of a 29-year-old patient contain the parasitic protozoa. It is established that they relate to the Sarcodina class. Specify these single-celled organisms:

Correct Answer: A

Rationale: The correct answer is A: Entamoeba gingivalis. Firstly, it is important to note that Entamoeba gingivalis is commonly found in the oral cavity, specifically in carious cavities. Secondly, Entamoeba gingivalis belongs to the Sarcodina class, which is characterized by their amoeboid movement using pseudopods. This protozoa is associated with oral health issues, particularly in individuals with poor oral hygiene. Now, let's analyze why the other choices are incorrect: B: Entamoeba histolutica is known for causing amoebic dysentery, not commonly associated with oral cavities. C: Entamoeba coli is typically found in the human large intestine, not in oral cavities. D: Amoeba proteus is a free-living amoeba commonly used in laboratory studies and not typically associated with oral cavity infections.

Question 6 of 9

An example of selective media is:

Correct Answer: A

Rationale: The correct answer is A: McConkey agar. Selective media selectively inhibit the growth of certain organisms while allowing others to grow. McConkey agar contains crystal violet and bile salts that inhibit the growth of Gram-positive bacteria, making it selective for Gram-negative bacteria. Choices B and C are not selective media, as they do not specifically inhibit the growth of certain types of bacteria. Choice D is incorrect as McConkey agar is indeed an example of selective media.

Question 7 of 9

A 32-year-old patient undergoing dental examination was found to have some rash-like lesions resembling secondary syphilis in the oral cavity. The patient was referred for the serological study with the purpose of diagnosis confirmation. In order to detect antibodies in the serum, living Treponema were used as diagnosticum. What serological test was performed?

Correct Answer: B

Rationale: The correct answer is B: Passive hemagglutination. In this test, red blood cells coated with Treponema antigens agglutinate in the presence of patient's serum antibodies. This indicates the presence of antibodies against Treponema, confirming the diagnosis. A: Immobilization test uses live Treponema to detect specific antibodies, but it is not commonly used for syphilis diagnosis. C: Precipitation test is not commonly used for syphilis diagnosis. D: Complement binding test is not specific for syphilis and is used more for autoimmune diseases. Therefore, passive hemagglutination is the most appropriate serological test in this case due to its specificity and relevance to the presentation of the patient.

Question 8 of 9

Bacteriological inspection of disinfection quality at a pharmacy revealed a microorganism in an utility room (in the sink). The microorganism has the following properties: mobile nonspore-forming gram- negative bacteria that form capsular substance, grow well on ordinary nutrient media, secrete the blue-green pigment. This microorganism is most likely to be of the following genus:

Correct Answer: A

Rationale: The correct answer is A: Pseudomonas. Rationale: 1. Mobile nonspore-forming gram-negative bacteria with a capsule substance indicate Pseudomonas. 2. Pseudomonas grow well on ordinary nutrient media, matching the description. 3. The secretion of a blue-green pigment is a characteristic feature of Pseudomonas. 4. Proteus is a gram-negative bacterium but does not match all the given properties. 5. Clostridium is a gram-positive bacterium that forms spores. 6. Shigella is a gram-negative bacterium but does not have the other characteristics mentioned. Therefore, based on the properties described, the most likely genus of the microorganism is Pseudomonas.

Question 9 of 9

Microscopical examination of an infiltrate removed from the submandibular skin area of a 30 y.o. man revealed foci of purulent fluxing surrounded by maturing granulations and mature connective tissue, the pus contains druses consisting of multiple short rod-like elements with one end attached to the homogenous centre. What disease is it?

Correct Answer: A

Rationale: The correct answer is A: Actinomycosis. This is supported by the presence of purulent foci with druses consisting of short rod-like elements attached to a homogenous center, which is characteristic of Actinomyces species. Actinomycosis commonly presents with granulation tissue and connective tissue formation. B: Tuberculosis does not typically present with druses containing short rod-like elements. C: Syphilis does not typically present with purulent foci or druses. D: Candidosis does not typically present with the described features of purulent fluxing and druses with short rod-like elements.

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