This describes the relationship of the blood concentration attained with initial dosing and the dose of drug given:

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ATI Intro to Pharmacology Quizlet Questions

Question 1 of 5

This describes the relationship of the blood concentration attained with initial dosing and the dose of drug given:

Correct Answer: D

Rationale: The volume of distribution (Vd) is a pharmacokinetic parameter that describes the relationship of the blood concentration attained with initial dosing and the dose of drug given. It is a theoretical volume that indicates the extent of drug distribution in the body relative to its concentration in the bloodstream. A high volume of distribution suggests that the drug is extensively distributed throughout the tissues of the body, while a low volume of distribution indicates that the drug is largely confined to the bloodstream. Therefore, Vd is the correct answer in this scenario.

Question 2 of 5

The nurse is caring for a well-known stage actor who has suddenly developed severe stage fright that is preventing him from working. What drug does the nurse suspect will be prescribed for this patient?

Correct Answer: D

Rationale: One of the indications for use of propranolol is prevention of stage fright, which is a sympathetic stress reaction to a particular situation. None of the other options are indicated for this use. The nurse should understand the indications for propranolol to ensure safe and effective administration.

Question 3 of 5

A patient taking SMZ/TMP asks the nurse what the name means. The nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?

Correct Answer: D

Rationale: SMZ/TMP (sulfamethoxazole/trimethoprim) works synergistically to inhibit bacterial folate synthesis at two different steps, making it effective against a broad spectrum of gram-positive and gram-negative organisms. It does not act as an anesthetic (A), displace trimethoprim (B), or increase excretion in the bladder (C). The combination enhances antibacterial activity and reduces the risk of resistance.

Question 4 of 5

A client is prescribed Colchicine. After taking three doses, the client complains of nausea, vomiting, and loose bowel stools. Which of the following should the client do?

Correct Answer: B

Rationale: Nausea, vomiting, and diarrhea are signs of colchicine toxicity, which can be life-threatening. The client should stop taking the medication and notify the physician immediately. Continuing the medication or adjusting the dose without medical advice can exacerbate the toxicity. Colchicine has a narrow therapeutic index, and close monitoring is required to prevent adverse effects.

Question 5 of 5

Biperiden hydrochloride (Akineton) is added to a list of antiparkinsonian medications that an elderly client is taking. Which of the following instructions made by the nurse that needs further learning?

Correct Answer: C

Rationale: Walking in the morning for direct sunlight is unrelated to the use of biperiden hydrochloride (Akineton) and does not address its side effects or therapeutic effects. Avoiding alcohol and caffeine, managing dry mouth, and increasing fiber and fluid intake are appropriate instructions. Therefore, the statement about sunlight indicates a need for further learning.

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