Thiazide diuretics may produce an increase in blood levels of uric acid and: *

Correct Answer: A

Rationale: Thiazide diuretics decrease urinary excretion of uric acid, leading to increased blood levels. Thiazides also increase potassium reabsorption, potentially causing hyperkalemia. However, the main effect on uric acid levels makes choice A correct. Choices B, C, and D are incorrect as thiazides do not directly impact BUN, urea, or glucose levels.

Correct Answer: C

Rationale: Acetazolamide is a carbonic anhydrase inhibitor commonly used in treating glaucoma due to its ability to decrease intraocular pressure. The drug works by reducing the production of aqueous humor in the eye. This mechanism makes it an effective treatment for glaucoma. In contrast, liver cirrhosis (choice A) is typically managed with diuretics that act on the kidneys to reduce fluid accumulation. CHF (choice B) is commonly treated with loop diuretics to reduce fluid overload and improve cardiac function. Acetazolamide is not indicated for treating heart failure. Kidney failure (choice D) may require diuretics to manage fluid balance, but acetazolamide is not the first-line treatment in this condition. Therefore, the correct answer is C, as acetazolamide's current indication is in the treatment of glaucoma.

Correct Answer: A

Rationale: The correct answer is A because erythropoietin, a hormone produced by the kidneys in the glomerular capsule, stimulates the production of red blood cells in the bone marrow. Choice B (the loop of Henle cells) is incorrect as they are involved in urine concentration, not hormone production. Choice C (pyramids of the kidney) is incorrect as they are structures in the kidney, not involved in hormone production. Choice D (adrenaline) is incorrect as it is produced by the adrenal glands, not the kidneys.

Correct Answer: D

Rationale: The correct answer is D: Acute glomerulonephritis. In this scenario, administering calcium is unwise with hyperkalemia because acute glomerulonephritis can lead to decreased glomerular filtration rate, which impairs the excretion of potassium. Calcium administration can worsen hyperkalemia by shifting potassium out of cells and into the bloodstream. Rhabdomyolysis (choice A) can cause hyperkalemia due to cell breakdown, and calcium may be beneficial to stabilize cell membranes. Nephrotoxic ATN (choice B) and ischemic ATN (choice C) are both conditions where calcium administration can help protect kidneys from further damage, but in acute glomerulonephritis, the risk of worsening hyperkalemia outweighs the potential benefits of calcium administration.

Correct Answer: C

Rationale: The correct answer is C because renal colic can present without hematuria. Renal colic is typically associated with severe flank pain caused by ureteral stones. Hematuria is a common symptom but not always present. This is due to the stone's location and size affecting the degree of irritation and damage to the urinary tract. Therefore, the absence of hematuria does not exclude the possibility of renal colic. Choices A, B, and D are incorrect. Females are not more commonly affected than males, calculi can be either radio-opaque or radio-lucent, and the recurrence rate by 5 years is closer to 50% rather than 20%.