The withdrawal syndrome is a combination of certain drug-specific symptoms that occur on sudden discontinuation of the drug. This syndrome is associated with:

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Pharmacology ATI Final Questions

Question 1 of 9

The withdrawal syndrome is a combination of certain drug-specific symptoms that occur on sudden discontinuation of the drug. This syndrome is associated with:

Correct Answer: D

Rationale: The withdrawal syndrome that occurs on sudden discontinuation of a drug is associated with both psychological dependence (choice A) and physical dependence (choice B).

Question 2 of 9

A pregnant woman is experiencing hypertension. The nurse knows that which drug is commonly used for a pregnant patient who is experiencing hypertension?

Correct Answer: D

Rationale: Methyldopa is the preferred antihypertensive medication for pregnant women experiencing hypertension. It has been extensively studied and considered safe for both the mother and the fetus. Methyldopa has been shown to effectively lower blood pressure in pregnant women without causing harm to the developing fetus. Other antihypertensive medications, such as Enalapril (Vasote) and Hydrochlorothiazide (HydroDIURIL), are contraindicated during pregnancy as they can cause harm to the fetus. Mannitol (Osmitrol) is an osmotic diuretic primarily used for reducing intracranial pressure or treating cerebral edema, not for hypertension in pregnancy. Therefore, Methyldopa is the right choice for a pregnant patient with hypertension.

Question 3 of 9

Rho(D) immune globulin (RhoGAM) is given to a pregnant woman after delivery and the nurse is giving information to the patient about the indication of the medication. The nurse determines that the patient understands the purpose of the medication if the patient tells that it will protect her baby from which of the following?

Correct Answer: D

Rationale: Rho(D) immune globulin (RhoGAM) is administered to Rh-negative mothers to prevent Rh incompatibility in future pregnancies. It works by preventing the mother's immune system from developing antibodies against Rh-positive fetal blood cells, which could harm subsequent Rh-positive babies. Pernicious anemia and German measles are unrelated to RhoGAM. The medication does not affect the baby's blood type but prevents the mother's immune response. Therefore, Rh incompatibility is the correct answer.

Question 4 of 9

When assessing a patient who is receiving a loop diuretic, the nurse looks for the manifestations of potassium deficiency, which would include what symptoms? (Select all that apply.)

Correct Answer: D

Rationale: Loop diuretics can cause potassium deficiency (hypokalemia), leading to symptoms such as muscle weakness. The other symptoms listed, including dyspnea, constipation, tinnitus, anorexia, and lethargy, are not typically associated with potassium deficiency.

Question 5 of 9

A 63-year-old man with glaucoma maintained on a regimen of topical medications with an exacerbation of his symptoms. He complains of difficulty with his vision in both eyes and has headaches. Which of the following drugs is the most appropriate treatment for this patient?

Correct Answer: C

Rationale: Glaucoma involves elevated intraocular pressure (IOP), and this patient's exacerbation-vision difficulty and headaches-requires effective IOP reduction. Bimatoprost and Latanoprost are prostaglandin analogs, increasing outflow, but may not act fast enough for acute worsening. Pilocarpine , a muscarinic agonist, contracts the ciliary muscle, opening the trabecular meshwork, enhancing aqueous humor outflow, and rapidly lowering IOP-ideal for this scenario. Tetracycline is an antibiotic, irrelevant. Travoprost (E), another prostaglandin, is similar to A and B. Pilocarpine's direct action on outflow makes it most appropriate for urgent IOP control in open-angle or angle-closure glaucoma exacerbation. Its side effects (miosis, brow ache) are tolerable given the need for immediate relief, distinguishing it from slower-acting prostaglandins.

Question 6 of 9

The withdrawal syndrome is a combination of certain drug-specific symptoms that occur on sudden discontinuation of the drug. This syndrome is associated with:

Correct Answer: D

Rationale: The withdrawal syndrome that occurs on sudden discontinuation of a drug is associated with both psychological dependence (choice A) and physical dependence (choice B).

Question 7 of 9

A 60-year-old woman has ulcerative colitis resistant to aminosalicylates and topical corticosteroids. It is decided to treat her with systemic corticosteroids. Which of the following is not a likely complication of the treatment?

Correct Answer: B

Rationale: Systemic corticosteroids (e.g., prednisone) for ulcerative colitis cause side effects. Osteoporosis results from reduced bone formation over time. Diabetes stems from glucocorticoid-induced hyperglycemia. Hypertension occurs via sodium retention and vasoconstriction. Mood changes are common due to CNS effects. Weight loss isn't typical; corticosteroids cause weight gain from increased appetite and fat redistribution, making it the exception. This reflects their metabolic impact, requiring monitoring in chronic use.

Question 8 of 9

A 26-year-old man with a chronic cough takes codeine for cough suppression. He presents to his primary care physician for follow-up. The patient admits to taking this medication three times daily even when he does not have symptoms. The treating physician must be concerned about which of the following effects?

Correct Answer: A

Rationale: Codeine, an opioid, risks addiction with frequent use. Diarrhea opposes its constipating effect. Euphoria and anxiety are possible but less concerning. Sweating (E) is minor. Addiction potential drives monitoring, given his overuse pattern.

Question 9 of 9

A patient has overdosed on Warfarin, what should be given to the patient to be reveresed?

Correct Answer: D

Rationale: Warfarin is an anticoagulant medication that works by inhibiting vitamin K-dependent clotting factors in the body. Overdosing on warfarin can lead to excessive bleeding due to the lack of functional clotting factors. To reverse the effects of warfarin overdose, Vitamin K is given because it helps the body restore the levels of clotting factors that were reduced by warfarin. Vitamin K promotes the synthesis of clotting factors II, VII, IX, and X, which allows the blood to clot effectively again. Therefore, in the case of a warfarin overdose, Vitamin K is the appropriate antidote to help reverse the anticoagulant effects.

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