The viral infection in the above question began in the respiratory tract. Which antibody class would best protect respiratory epithelial cells from viral infection?

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NCLEX Pediatric Immunization Questions Questions

Question 1 of 5

The viral infection in the above question began in the respiratory tract. Which antibody class would best protect respiratory epithelial cells from viral infection?

Correct Answer: A

Rationale: IgA is the primary antibody protecting mucosal surfaces like the respiratory tract.

Question 2 of 5

A 5-year-old boy presents with his third episode of painful cervical lymphadenitis. Each was treated with incision and drainage and grew Staphylococcus aureus. At the age of 2 years, he required surgical aspiration of a liver abscess. The most important laboratory test is

Correct Answer: B

Rationale: The nitroblue tetrazolium (NBT) test assesses the ability of neutrophils to produce a respiratory burst, which is defective in chronic granulomatous disease (CGD). The history of recurrent Staphylococcus aureus infections and a liver abscess strongly suggests CGD, making the NBT test the most important diagnostic tool.

Question 3 of 5

Of the following, the findings that are MOST suggestive of DiGeorge syndrome are

Correct Answer: D

Rationale: Hypocalcemia (from parathyroid hypoplasia) and congenital heart defects are hallmark features of DiGeorge syndrome due to thymic and parathyroid underdevelopment.

Question 4 of 5

The highest white blood cells count is seen at

Correct Answer: B

Rationale: WBC counts peak at 12 hours of life (up to 20,000-30,000/μL) due to stress of birth, then decline over time.

Question 5 of 5

Leukemoid reactions (WBC count >50,000/μL) are characterized by abundant

Correct Answer: D

Rationale: Leukemoid reactions show a left shift with mature and immature neutrophils (e.g., metamyelocytes), unlike leukemia, which has blasts.

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