ATI RN
Clinical Pharmacology of Cardiovascular Drugs PPT Questions
Question 1 of 5
The use of heparin is recommended for treatment of deep venous thrombosis. This statement is:
Correct Answer: A
Rationale: The correct answer is A: TRUE. Heparin is recommended for the treatment of deep venous thrombosis (DVT) because it prevents further clot formation and helps dissolve existing clots. Heparin works by inhibiting the formation of blood clots. Other choices (B, C, D) are incorrect because they do not align with the established medical guidelines for DVT treatment.
Question 2 of 5
This drug is a potassium channel activator:
Correct Answer: C
Rationale: Step-by-step rationale: 1. Diazoxide is a potassium channel activator that works by opening ATP-sensitive potassium channels in smooth muscle cells. 2. This action leads to hyperpolarization of the cell membrane, resulting in relaxation of vascular smooth muscle. 3. This vasodilatory effect is beneficial in conditions like hypertension and hypoglycemia. 4. Nifedipine (A) is a calcium channel blocker, Saralasin (B) is an angiotensin II receptor antagonist, and Losartan (D) is an angiotensin II receptor blocker. Summary: - Nifedipine does not activate potassium channels. - Saralasin and Losartan do not have a direct effect on potassium channels. - Diazoxide is the correct choice as it specifically activates potassium channels to induce vasodilation.
Question 3 of 5
Hypothalamic and pituitary hormones (and their synthetic analogs) have pharmacologic applications in three areas EXCEPT the following:
Correct Answer: D
Rationale: The correct answer is D: As food supplements. Hypothalamic and pituitary hormones are not used as food supplements because they are potent molecules with specific regulatory functions in the body. Step 1: Replacement therapy (Choice A) involves providing hormones to individuals with hormone deficiency states to restore normal physiologic levels. This is a common pharmacologic application of these hormones. Step 2: Drug therapy (Choice B) involves using synthetic analogs of these hormones at pharmacologic doses to treat various disorders by eliciting specific hormonal effects that may not occur at physiologic levels. Step 3: Diagnostic tool (Choice C) involves using these hormones in stimulation tests to assess the functioning of the endocrine system by observing the response to hormonal stimulation. In summary, choices A, B, and C all represent valid pharmacologic applications of hypothalamic and pituitary hormones, while choice D (food supplements) is the exception as these hormones are not meant to be consumed as dietary
Question 4 of 5
The action of insulin is potentiated by:
Correct Answer: C
Rationale: The correct answer is C: Biguanides. Biguanides, such as metformin, potentiate the action of insulin by improving insulin sensitivity in tissues, reducing hepatic glucose production, and enhancing peripheral glucose uptake. Sulphonylureas (A) stimulate insulin secretion, glucagon (B) increases blood glucose levels, and D is incorrect as biguanides do potentiate insulin action.
Question 5 of 5
Which of the following property combinations is peculiar to the majority of NSAIDs?
Correct Answer: C
Rationale: The correct answer is C (Antipyretic, analgesic, anti-inflammatory) for NSAIDs. NSAIDs primarily work by inhibiting COX enzymes, reducing inflammation, pain, and fever. A is incorrect because not all NSAIDs have antihistaminic properties. B is incorrect because NSAIDs are not typically immunodepressive. D is incorrect because antihistaminic properties are not common in NSAIDs. In summary, the unique combination of antipyretic, analgesic, and anti-inflammatory properties is peculiar to the majority of NSAIDs.