ATI RN
ATI Hematologic System Test Questions
Question 1 of 5
The typical Reed-Sternberg cells are either infrequent or absent. Instead, lymphocytic and histiocytic cells or 'popcorn cells' are seen within a background of inflammatory cells, which are predominantly benign lymphocytes. Which type of Hodgkin's lymphoma best suit the description?
Correct Answer: D
Rationale: Rationale for Choice D (Lymphocyte predominance): 1. Reed-Sternberg cells are infrequent or absent in lymphocyte predominance Hodgkin's lymphoma. 2. 'Popcorn cells' are seen in lymphocyte predominance Hodgkin's lymphoma. 3. Predominance of benign lymphocytes in the background is characteristic of lymphocyte predominance Hodgkin's lymphoma. Summary of other choices: A: Nodular sclerosis - Characterized by collagen bands dividing lymph node into nodules, not 'popcorn cells'. B: Mixed cellularity - Reed-Sternberg cells present, not 'popcorn cells'. C: Lymphocyte depleted - Few to no lymphocytes seen, not benign lymphocytes as described in the question.
Question 2 of 5
Bone marrow responds to iron therapy by increasing erythropoietic activity. Which of the following in bone marrow would most likely indicate erythropoiesis?
Correct Answer: B
Rationale: Rationale: 1. Bone marrow increases erythropoiesis in response to iron therapy. 2. Reticulocytes are immature red blood cells derived from erythroblasts, indicating active erythropoiesis. 3. Myelocytes are precursors of granulocytes, not involved in erythropoiesis. 4. Ring sideroblasts are abnormal erythroblasts with iron granules, not indicative of active erythropoiesis. 5. Target cells are red blood cells with central "target-like" appearance due to excess membrane, not directly related to erythropoiesis.
Question 3 of 5
Dohle bodies are patches of dilated endoplasmic reticulum that appear as cerulean blue cytoplasmic puddles. These findings are mostly seen in
Correct Answer: D
Rationale: Step-by-step rationale for why choice D (Infectious mononucleosis) is correct: 1. Infectious mononucleosis is caused by the Epstein-Barr virus. 2. Dohle bodies are seen in the peripheral blood of patients with infectious mononucleosis. 3. These bodies represent aggregates of rough endoplasmic reticulum in neutrophils. 4. The appearance of Dohle bodies is attributed to the viral infection in infectious mononucleosis. Summary: A: Chronic myeloid leukemia - Dohle bodies are not typically seen in this condition. B: Leukemoid reaction - Dohle bodies are not specific to a leukemoid reaction. C: Chediak-Higashi syndrome - This syndrome is characterized by giant granules in neutrophils, not Dohle bodies.
Question 4 of 5
The main vector transmitting malaria in Sabah is Anopheles balabacensis. This vector breeds in
Correct Answer: C
Rationale: The correct answer is C: Temporary collecting of water in jungles. Anopheles balabacensis is a forest-dwelling mosquito species commonly found in jungle environments. They prefer to breed in temporary water collections such as rainwater puddles, small ponds, or stream edges within the jungle. Breeding in urban areas, drains, or rock pools would not be typical for this species based on its natural habitat preference. Therefore, the most suitable breeding site for this vector in Sabah would be temporary water collections in jungles.
Question 5 of 5
The commonest cause of jaundice in thalassemia is:
Correct Answer: D
Rationale: The correct answer is D: haemolysis. In thalassemia, there is an abnormality in hemoglobin production leading to the destruction of red blood cells, causing hemolysis. This results in the release of bilirubin, leading to jaundice. Iron deposition in the liver (choice B) is seen in conditions like hemochromatosis, not thalassemia. Viral hepatitis B and C (choices A and C) can cause jaundice, but they are not the commonest cause in thalassemia patients, as hemolysis is the primary mechanism in this population.