The transporter associated with antigen presentation (TAP) the peptides to traverse the membrane bilayer of the endoplasmic reticulum and bind in the empty peptide-binding groove of nascent MHC molecules being synthesized in the endoplasmic reticulum.

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Pediatric Immunization NCLEX Questions Questions

Question 1 of 5

The transporter associated with antigen presentation (TAP) the peptides to traverse the membrane bilayer of the endoplasmic reticulum and bind in the empty peptide-binding groove of nascent MHC molecules being synthesized in the endoplasmic reticulum.

Correct Answer: A

Rationale: TAP transports peptides into the ER for loading onto MHC Class I, not Class II.

Question 2 of 5

Phagocytose, bacteriocidal activity, ADCC

Correct Answer: B

Rationale: Neutrophils phagocytose bacteria and perform ADCC.

Question 3 of 5

In the embryonic human, the primary lymphoid organs are initially in the yolk sac, then in the fetal , and finally in the

Correct Answer: D

Rationale: Hematopoiesis shifts from yolk sac to fetal spleen/liver, then bone marrow/thymus.

Question 4 of 5

Which of the following locations has cell that transport the antigens by transcytosis into sub-epithelial tissues (e.g. lamina propria) where they encounter lymphocytes?

Correct Answer: C

Rationale: Peyer's patches in GALT use M cells for transcytosis.

Question 5 of 5

Which of the following has the surface marker CD34 instead of the surface marker CD19, during B cell development?

Correct Answer: A

Rationale: CD34 is on hematopoietic stem cells; CD19 appears at the pro-B stage.

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