The thyroid hormones are transported in plasma bound to thyroxine-binding globulin (TBG), a glycoprotein synthesized in the liver. TBG binds approximately 70% of T4 and 50% of T3. TBG level increase with administration of

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Pediatric Endocrine System Questions

Question 1 of 5

The thyroid hormones are transported in plasma bound to thyroxine-binding globulin (TBG), a glycoprotein synthesized in the liver. TBG binds approximately 70% of T4 and 50% of T3. TBG level increase with administration of

Correct Answer: A

Rationale: Estrogens (A) increase TBG levels, raising bound thyroid hormone.

Question 2 of 5

Chronic lymphocytic thyroiditis is the most common cause of acquired hypothyroidism, with or without goiter. All the following are true EXCEPT

Correct Answer: D

Rationale: The clinical course of chronic lymphocytic thyroiditis (Hashimoto’s) varies (not constant, D), with remission and progression possible.

Question 3 of 5

Hypocalcemia is common in neonates between 12 and 72 hr of life, especially in infants with

Correct Answer: D

Rationale: Hypomagnesemia (D) strongly correlates with neonatal hypocalcemia due to impaired PTH release.

Question 4 of 5

Parathyroid crisis is manifested by the following EXCEPT

Correct Answer: B

Rationale: Progressive polyuria (B) is not typical of hypercalcemic crisis; it’s more associated with diabetes insipidus.

Question 5 of 5

The MOST common cause of primary adrenal insufficiency in infancy is

Correct Answer: A

Rationale: Congenital adrenal hyperplasia (A), especially 21-hydroxylase deficiency, is the most common cause in infancy.

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