ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by
Correct Answer: B
Rationale: Sulfasalazine breaks down into 5-ASA in the colon, which locally suppresses inflammation in ulcerative colitis.
Question 2 of 5
Trimethoprim inhibits bacteria without affecting mammalian cells because
Correct Answer: B
Rationale: Trimethoprim selectively inhibits bacterial dihydrofolate reductase due to its higher affinity, sparing mammalian cells.
Question 3 of 5
Select the antimicrobial drug which is used orally only for urinary tract infection for bacterial diarrhoeas
Correct Answer: D
Rationale: Nalidixic acid is used orally for UTIs and some bacterial diarrheas, concentrating in urine with limited systemic effect.
Question 4 of 5
Acidic urine augments the antibacterial action of the following drug
Correct Answer: D
Rationale: Nitrofurantoin’s antibacterial action is enhanced in acidic urine, increasing its efficacy against UTI pathogens.
Question 5 of 5
Occurrence of the following adverse reaction absolutely contraindicates further use of rifampin in the treatment of tuberculosis
Correct Answer: C
Rationale: Flu-like syndrome with rifampin is a severe hypersensitivity reaction, contraindicating further use.