ATI RN
Pediatric Immunizations NCLEX Questions Questions
Question 1 of 5
The TCR binds with , and the relatively surface of the TCR interacts with its ligand.
Correct Answer: D
Rationale: The TCR binds both MHC and peptide antigen with a flat surface for recognition.
Question 2 of 5
Which of the following is NOT a structural chain in class I MHC?
Correct Answer: A
Rationale: Class I MHC includes α1, α2, α3, and β2-microglobulin, but not β1.
Question 3 of 5
Which of the following is true regarding immunoglobulin and T-cell receptor (TCR) proteins and gene segments?
Correct Answer: A
Rationale: Heavy chains (VDJ) are analogous to β/δ TCR chains; light chains (VJ) are analogous to α/γ TCR chains.
Question 4 of 5
The invariant chain the empty peptide-binding groove. After vesicle fusion, the invariant chain is and peptides can enter the MHC class II grove.
Correct Answer: D
Rationale: The invariant chain blocks the MHC Class II groove to prevent premature peptide binding and is degraded after vesicle fusion to allow peptide loading.
Question 5 of 5
Which of the following is the correct order for a lymphocyte to be activated?
Correct Answer: B
Rationale: Lymphocyte activation follows: antigen recognition, receptor clustering, tyrosine kinase activation, and phosphorylation.