ATI RN
ATI Intro to Pharmacology Quizlet Questions
Question 1 of 5
The student nurse has completed an initial pharmacology course and tells the nursing instructor that it was difficult and she is glad it is over. What is the best response by the nursing instructor?
Correct Answer: B
Rationale: Pharmacology's complexity means learning is ongoing-new drugs, research, and applications evolve, preventing full mastery and requiring continuous growth. Applying knowledge is true but assumes completion. Painful learning dismisses positivity. Graduate courses are premature. Gradual learning reflects the field's dynamic nature, preparing the student for lifelong education, a realistic and encouraging perspective.
Question 2 of 5
The physician has prescribed sertraline (Zoloft) for the patient who is anxious and depressed. The patient calls the nurse to report that he has experienced delayed ejaculation since being on this medication. What is the best response by the nurse?
Correct Answer: B
Rationale: Sertraline, an SSRI, often causes sexual side effects like delayed ejaculation-common, per patient data-but depression treatment outweighs this for now. Switching is an option, not immediate. Suicide risk from stopping is possible but not assumed. It rarely resolves alone-management varies. Prioritizing depression balances care, per guidelines.
Question 3 of 5
A 42-year-old woman with a 1-year history of rheumatoid arthritis comes to see her primary care physician complaining of worsening symptoms. She has been taking leflunomide. IL-1 and TNF-α are two key cytokines involved in the negative sequelae of rheumatoid arthritis. Which of the following drugs is a recombinant form of an endogenous IL-1 antagonist?
Correct Answer: B
Rationale: RA involves IL-1 and TNF-α driving inflammation. The question seeks a recombinant IL-1 antagonist. Abatacept inhibits T-cell costimulation, not IL-1. Anakinra , a recombinant IL-1 receptor antagonist (IL-1Ra), blocks IL-1 signaling, matching the description. Methotrexate slows cell proliferation, not an IL-1 antagonist. Hydroxychloroquine modulates immunity differently. Rituximab (E) targets B cells. Anakinra mimics natural IL-1Ra, reducing joint damage in RA when leflunomide fails, directly countering IL-1's effects, unlike broader or unrelated mechanisms of other options.
Question 4 of 5
A 24-year-old man is admitted for an emergent appendectomy. While in the operating room, the anesthesiologist finds that he must use a much higher than expected anesthetic dose to anesthetize this patient. After the surgery, the patient admits to barbiturate abuse. What is the correct term for the fact that his history of barbiturate abuse led to a greater anesthetic requirement?
Correct Answer: C
Rationale: Barbiturate abuse increases anesthetic need due to cross-tolerance . Chronic use induces enzymes and receptor changes, reducing anesthetic efficacy. Addiction , dependence , and cross-dependence don't explain dosing. Tolerance (E) is drug-specific. Cross-tolerance fits this scenario.
Question 5 of 5
A 48-year-old woman with obsessive-compulsive disorder presents to her primary care physician for evaluation. She states that her symptoms have worsened during the last 6 months and desires treatment. She has begun on sertraline. Which of the following precautions must be exercised by the physician?
Correct Answer: D
Rationale: Sertraline, an SSRI, risks suicidal tendencies , especially early in treatment for OCD. Hepatic carcinoma , volume overload , and antibiotic potentiation aren't concerns. FDA warnings highlight this risk, necessitating monitoring in this worsening case.