ATI RN
Pharmacology ATI Final Questions
Question 1 of 5
The student nurse has been reading about the Human Genome Project and asks the nursing instructor how this will impact future pharmacological therapies. What is the best response by the instructor?
Correct Answer: D
Rationale: The Human Genome Project enables pharmacogenomics, tailoring drugs to genetic profiles for better efficacy (e.g., CYP2D6 variants), not eliminating drugs. Standardized doses ignore genetics. Disease prevention via genes complements, not replaces, drugs. Individualized therapy leverages genomics, enhancing treatment precision.
Question 2 of 5
A 63-year-old man with glaucoma maintained on a regimen of topical medications with an exacerbation of his symptoms. He complains of difficulty with his vision in both eyes and has headaches. Which of the following drugs is the most appropriate treatment for this patient?
Correct Answer: C
Rationale: Glaucoma involves elevated intraocular pressure (IOP), and this patient's exacerbation-vision difficulty and headaches-requires effective IOP reduction. Bimatoprost and Latanoprost are prostaglandin analogs, increasing outflow, but may not act fast enough for acute worsening. Pilocarpine , a muscarinic agonist, contracts the ciliary muscle, opening the trabecular meshwork, enhancing aqueous humor outflow, and rapidly lowering IOP-ideal for this scenario. Tetracycline is an antibiotic, irrelevant. Travoprost (E), another prostaglandin, is similar to A and B. Pilocarpine's direct action on outflow makes it most appropriate for urgent IOP control in open-angle or angle-closure glaucoma exacerbation. Its side effects (miosis, brow ache) are tolerable given the need for immediate relief, distinguishing it from slower-acting prostaglandins.
Question 3 of 5
A 60-year-old woman has ulcerative colitis resistant to aminosalicylates and topical corticosteroids. It is decided to treat her with systemic corticosteroids. Which of the following is not a likely complication of the treatment?
Correct Answer: B
Rationale: Systemic corticosteroids (e.g., prednisone) for ulcerative colitis cause side effects. Osteoporosis results from reduced bone formation over time. Diabetes stems from glucocorticoid-induced hyperglycemia. Hypertension occurs via sodium retention and vasoconstriction. Mood changes are common due to CNS effects. Weight loss isn't typical; corticosteroids cause weight gain from increased appetite and fat redistribution, making it the exception. This reflects their metabolic impact, requiring monitoring in chronic use.
Question 4 of 5
The nurse is reviewing the plan of care for a patient receiving enteral therapy. What is the most common complication of enteral therapy?
Correct Answer: C
Rationale: Diarrhea is the most common complication of enteral therapy, often due to formula composition, administration rate, or bacterial contamination. Aspiration (A) is a serious but less common complication. Constipation (B) and muscle weakness (D) are not typically associated with enteral therapy.
Question 5 of 5
When a patient is receiving diuretic therapy, which of these assessment measures would best reflect the patient™s fluid volume status?
Correct Answer: C
Rationale: When a patient is receiving diuretic therapy, monitoring intake, output, and daily weight is essential in assessing the patient's fluid volume status. Diuretics promote the excretion of excess fluid from the body, which can lead to changes in fluid balance. Monitoring intake and output provides information about how much fluid the patient is taking in and how much is being excreted, helping to assess the overall fluid balance. Daily weight measurements can also indicate changes in fluid status, as a sudden weight gain or loss may suggest fluid retention or depletion, respectively. Additionally, trends in weight changes over time can provide valuable information about the effectiveness of diuretic therapy and the patient's response to treatment.