ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
The spleen has a red pulp (macrophages and red blood cells) and a white pulp (dense lymphoid tissue). T cells are found chiefly in the and B cells are found in the both within the pulp.
Correct Answer: A
Rationale: T cells are in PALS, B cells in follicles, both in white pulp.
Question 2 of 5
During B cell development, at what stage is membrane bound IgM found?
Correct Answer: D
Rationale: Membrane-bound IgM is expressed on immature B cells.
Question 3 of 5
Where does affinity maturation occur?
Correct Answer: B
Rationale: Affinity maturation occurs in germinal centers during the immune response.
Question 4 of 5
At what stage are rearranged TCRs expressed on the cell surface?
Correct Answer: B
Rationale: Rearranged TCRs are first expressed at the DP stage for selection.
Question 5 of 5
IFN-γ stimulates ___ immunity by enhancing ___ T cells as well as activating macrophages and natural killer cells. IL-4/IL-5 stimulate ___ immunty (antibodies) by activating B cells and eosinophils and induce ___-type responses.
Correct Answer: B
Rationale: IFN-γ boosts cell-mediated immunity via CD4+ T cells; IL-4/IL-5 drive humoral immunity with IgE.