ATI RN
microbiology test bank Questions
Question 1 of 5
The actual genetic makeup of an organism is referred to as its
Correct Answer: B
Rationale: The correct answer is B: genotype. The genotype refers to the actual genetic makeup of an organism, including all the genes and alleles present in its DNA. This determines the traits and characteristics of an organism. Phenotype (A) is the observable physical or biochemical characteristics of an organism. Conjugation (C) is a process in bacteria involving the transfer of genetic material. Construct (D) is not a term related to genetics. Therefore, the correct choice is B as it specifically refers to the genetic composition of an organism.
Question 2 of 5
Ebola viruses need to be handled in which of the following biosafety levels?
Correct Answer: D
Rationale: The correct answer is D: BSL4. Ebola viruses are highly infectious and pose a high risk to laboratory workers. BSL4 facilities are designed to handle agents that pose a severe threat to human health and have no available vaccines or treatments. These facilities have strict guidelines for handling infectious agents, including full-body suits, negative air pressure, and decontamination processes to prevent any possible exposure. BSL1, BSL2, and BSL3 are not adequate for handling Ebola viruses due to their lower levels of containment and safety measures.
Question 3 of 5
A 5-year-old kindergartener has diphtheria. To find the carriers of the disease among the kindergarten staff, samples of pharyngeal mucus were obtained from the employers. One of the employers had gram-positive bacilli in her sample. They were situated at an angle to each other and colored unevenly, when stained according to Loeffler. What method can confirm that this carrier is dangerous to other people?
Correct Answer: A
Rationale: The correct answer is A: Toxin production test. Rationale: 1. Diphtheria is caused by a toxin produced by Corynebacterium diphtheriae. 2. To confirm if the carrier is dangerous, we need to test if they are producing the toxin. 3. The toxin production test directly assesses if the bacteria are producing the harmful toxin. 4. Positive results indicate the carrier is dangerous and can transmit the disease to others. Summary of other choices: B: Mouse neutralization test - Used to detect diphtheria antitoxin levels in blood, not to confirm if the carrier is dangerous. C: Immunofluorescence test - Used to detect specific antigens or antibodies, not directly related to confirming the carrier's danger. D: Complement fixation test - Measures immune response, not specific to toxin production confirmation.
Question 4 of 5
A patient was diagnosed with active focal pulmonary tuberculosis. What drug should be prescribed in the first place?
Correct Answer: A
Rationale: The correct answer is A: Isoniazid. Isoniazid is a first-line drug for treating active pulmonary tuberculosis due to its high efficacy and low toxicity. It works by inhibiting the synthesis of mycolic acids in the bacterial cell wall. Sulfalen, Cyclocerine, and Ethionamide are not first-line drugs for tuberculosis. Sulfalen is used for urinary tract infections, Cyclocerine for drug-resistant tuberculosis, and Ethionamide as a second-line drug for multidrug-resistant tuberculosis. Therefore, Isoniazid is the most appropriate initial choice for treating active focal pulmonary tuberculosis.
Question 5 of 5
First-year schoolchildren have received tuberculin skin test (Mantoux test) at the school nurse's office. The purpose of this test was:
Correct Answer: D
Rationale: The correct answer is D: To determine the children that need to receive BCG vaccination. The Mantoux test is used to identify individuals who have been exposed to Tuberculosis (TB) and need BCG vaccination for protection. Parotitis (choice A) is a viral infection unrelated to TB. Allergization rate toward rickettsia (choice B) and immune stress toward diphtheria (choice C) are not related to the Mantoux test or BCG vaccination. Therefore, choice D is the correct answer as it aligns with the purpose of the Mantoux test.