The signs and symptoms of congenital adrenal hyperplasia (salt wasting form of the disease) caused by 21-hydroxylase deficiency typically first develop in affected infants at approximately

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Pediatric Endocrine System Questions

Question 1 of 5

The signs and symptoms of congenital adrenal hyperplasia (salt wasting form of the disease) caused by 21-hydroxylase deficiency typically first develop in affected infants at approximately

Correct Answer: B

Rationale: Salt-wasting CAH symptoms typically appear at 1-2 weeks (B) due to aldosterone deficiency.

Question 2 of 5

True gynecomastia is characterized by the presence of a palpable fibroglandular mass (located concentrically beneath the nipple and areolar region) at least

Correct Answer: D

Rationale: True gynecomastia requires a mass ≥2 cm (D) to distinguish from pseudogynecomastia.

Question 3 of 5

The 47,XXX (trisomy) chromosomal constitution is the most frequent extra-X chromosome abnormality in females, occurring in almost 1 in 1,000 liveborn females. It is characterized by the following EXCEPT

Correct Answer: C

Rationale: 47,XXX females typically have normal sexual development (not delayed, C).

Question 4 of 5

The following factors are implicated in the pathogenesis of type 1 DM EXCEPT

Correct Answer: D

Rationale: Excessive infection exposure (D) is not a risk factor; limited exposure may increase autoimmunity risk.

Question 5 of 5

Any child with diabetic ketoacidosis (DKA) can be easily transitioned to oral intake and subcutaneous insulin when the following criteria are found EXCEPT

Correct Answer: B

Rationale: Transition requires pH >7.30 (not 7.25, B) to ensure acidosis resolution.

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