The serum alpha-fetoprotein (AFP) level is elevated with some malignant germ cell tumors (GCTs) especially endodermal sinus tumors; it can be used as a measure of treatment response and during follow-up after completion of chemotherapy. However, it is normally elevated during infancy. At which age does AFP physiologically fall to normal adult level?

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Question 1 of 5

The serum alpha-fetoprotein (AFP) level is elevated with some malignant germ cell tumors (GCTs) especially endodermal sinus tumors; it can be used as a measure of treatment response and during follow-up after completion of chemotherapy. However, it is normally elevated during infancy. At which age does AFP physiologically fall to normal adult level?

Correct Answer: C

Rationale: The correct answer is C) one year. The physiological decrease of serum alpha-fetoprotein (AFP) levels to normal adult levels occurs by one year of age. During infancy, AFP levels are typically elevated but gradually decrease as the child grows. This normalization of AFP levels by one year is important to understand when interpreting lab results in pediatric patients. Option A) three months is incorrect because AFP levels do not fall to normal adult levels by this age. Option B) eight months is also incorrect as the physiological decrease to adult levels has not occurred by this time. Option D) three years is incorrect as AFP levels should normalize by one year, not by three years. Understanding the age at which AFP levels should reach adult levels is crucial for pediatric healthcare providers to accurately assess treatment response and monitor for recurrence in patients with malignant germ cell tumors. This knowledge aids in making informed clinical decisions and providing optimal care for pediatric patients.

Question 2 of 5

Prenatal exposure to cigarette smoke is associated with

Correct Answer: D

Rationale: In this scenario, the correct answer is D) neonatal diabetes. Prenatal exposure to cigarette smoke is associated with an increased risk of neonatal diabetes due to the harmful chemicals and toxins present in tobacco smoke that can disrupt normal fetal development, potentially affecting the pancreas and insulin production in the newborn. Option A) shorter neonatal length and Option B) lower birthweight are commonly associated with maternal smoking during pregnancy, but they are not directly linked to neonatal diabetes. These outcomes are more related to restricted fetal growth and development due to the vasoconstrictive effects of nicotine and carbon monoxide in cigarettes. Option C) changes in neonatal behavior can also be a consequence of prenatal exposure to cigarette smoke, as nicotine can cross the placenta and affect the developing brain, leading to alterations in behavior. However, this is not specifically linked to neonatal diabetes. In an educational context, understanding the implications of prenatal exposure to cigarette smoke on neonatal health is crucial for healthcare professionals working with pregnant women and newborns. It highlights the importance of smoking cessation interventions during pregnancy to reduce the risk of adverse outcomes for both the mother and the baby. Educating expectant mothers about the dangers of smoking and providing support for quitting can help improve maternal and neonatal health outcomes.

Question 3 of 5

Regarding physical growth of preschool children (3-5 years), all are true EXCEPT

Correct Answer: A

Rationale: The correct answer for this question is option A) 7-8 kg weight increment/yr is not true for preschool children (3-5 years). Option A is incorrect because preschool children typically gain around 2-3 kg (4.4-6.6 lbs) per year, not 7-8 kg. Rapid weight gain is more common in infancy than during the preschool years. Preschool children are usually more active and their growth rate slows down compared to infants. Option B is correct as children usually have around 20 primary teeth erupted by the age of 3 years. This is a normal developmental milestone for preschoolers. Option C is incorrect as brain myelination, the process of forming a protective sheath around nerves, continues well beyond 8 years of age. Myelination is a crucial process for the proper functioning of the nervous system and continues into adolescence and early adulthood. Option D is incorrect because the average height increment per year for preschool children is around 6-7 cm, not 5-6 cm. The growth rate varies throughout childhood, with a rapid growth spurt typically occurring during adolescence. In an educational context, understanding the typical growth and development milestones of preschool children is essential for healthcare professionals working with this age group. By knowing what is considered normal for this age range, healthcare providers can monitor children's growth, detect any deviations from the norm, and provide appropriate interventions if needed. This knowledge also helps in educating parents and caregivers about what to expect in terms of physical growth during the preschool years.

Question 4 of 5

The child begins to understand right and left by age of

Correct Answer: C

Rationale: The correct answer to the question "The child begins to understand right and left by the age of 5 years" is option C. Understanding right and left involves the development of spatial awareness and directionality, which is a complex cognitive skill that typically emerges around the age of 5 in children. At this age, most children have developed the neurological connections necessary to differentiate between right and left consistently. Option A (3 years) is incorrect because at age 3, children are still in the early stages of cognitive development and may not have fully grasped the concept of right and left consistently. Option B (4 years) is also incorrect because while some children may start to understand right and left at this age, it is more commonly mastered by age 5. Option D (6 years) is incorrect as by this age, most children should have already developed a clear understanding of right and left. In an educational context, understanding the typical developmental milestones related to spatial awareness in children is crucial for pediatric nurses. By knowing when children are expected to master concepts like right and left, nurses can better assess and support a child's cognitive development during health assessments and interventions. This knowledge also helps nurses communicate effectively with children and their caregivers, enhancing the quality of care provided.

Question 5 of 5

Potential sources of mercury include all of the following EXCEPT

Correct Answer: D

Rationale: The correct answer is D) milk. Mercury is a toxic heavy metal that can be found in various sources. Swordfish, old teething powders, and quicksilver are all potential sources of mercury exposure. Swordfish is known to contain high levels of mercury due to bioaccumulation in large predatory fish. Old teething powders may have contained mercury prior to regulations banning its use in consumer products. Quicksilver is another term for elemental mercury, a common form of mercury found in certain products. In the context of pediatric health, it is crucial for healthcare professionals to be aware of potential sources of mercury exposure as children are more vulnerable to the harmful effects of mercury toxicity. Educating parents about these sources can help prevent accidental exposure and protect children from adverse health outcomes. Monitoring dietary intake, especially of fish known to have high mercury levels, and avoiding products like old teething powders can reduce the risk of mercury exposure in children.

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