The role of adhesins in gram positive bacteria is carried out by:

Correct Answer: A

Rationale: Adhesins in gram positive bacteria are typically carried out by surface structures such as lipoteichoic acids. These molecules help the bacteria adhere to host cells or tissues. Lipoteichoic acids are specific to gram positive bacteria and play a crucial role in initiating infections. Fimbriae, flagella, and short chain mycolic acids are not primarily responsible for adhesion in gram positive bacteria. Fimbriae are more commonly found in gram negative bacteria, flagella are involved in motility, and short chain mycolic acids are specific to mycobacteria. Therefore, the correct answer is A, lipoteichoic acids.

Correct Answer: B

Rationale: I'm sorry, but there seems to be a mistake in the question provided. The correct answer should be A: smallpox. Variola virus indeed causes smallpox, not jock itch. Smallpox is a highly contagious disease characterized by fever and rash, while jock itch, ringworm, and shingles are caused by different pathogens and have distinct symptoms.

Correct Answer: D

Rationale: The correct answer is D because polio viruses are primarily found in the gastrointestinal tract and respiratory secretions. Feces, nasopharyngeal swabs, and cerebrospinal fluid are the most suitable materials for isolating polio viruses due to their presence in these body fluids. Feces contain the virus shed from the intestines, nasopharyngeal swabs collect respiratory secretions where the virus may be present, and cerebrospinal fluid is important for detecting the virus in cases of neurological complications. Choices A and B include irrelevant body fluids that are not typically associated with polio virus transmission. Option C is too limited as the virus can also be present in respiratory secretions and cerebrospinal fluid, not just feces.

Correct Answer: C

Rationale: The correct answer is C because there is no obligatory vaccine for Neisseria meningitidis in Bulgaria. The rationale for this is that while vaccines are available for meningococcal disease, they are not mandatory in Bulgaria. Therefore, this statement is incorrect. A: This statement is correct as Waterhouse-Friderichsen syndrome can occur during meningococcemia due to rapid progression of the infection leading to adrenal gland failure. B: This statement is incorrect as Neisseria meningitidis is most common in infants, children, and adolescents, with a second peak in young adults. D: This statement is correct as Neisseria meningitidis is transmitted through respiratory secretions, such as coughing or kissing, especially in close contacts like household members or roommates.

Correct Answer: D

Rationale: The correct answer is D: interferes with protein synthesis. Cephalosporins are beta-lactam antibiotics that work by inhibiting bacterial cell wall synthesis, not protein synthesis. They are bactericidal and have a relatively broad spectrum of activity against various bacteria. Choice A, B, and C all describe characteristics of cephalosporins, making them incorrect options.

Correct Answer: A

Rationale: The correct answer is A: BK virus. BK virus is a common cause of hemorrhagic cystitis, especially in immunocompromised individuals. It infects the urinary tract, leading to inflammation and bleeding in the bladder. Enteroviruses, Flaviviruses, and Coronaviruses do not typically cause hemorrhagic cystitis. Enteroviruses usually cause respiratory and gastrointestinal infections, Flaviviruses are commonly associated with diseases like dengue fever and Zika virus, and Coronaviruses are known for causing respiratory illnesses such as COVID-19. Hence, the correct answer is A as it is the only virus among the options known to cause hemorrhagic cystitis.

Correct Answer: B

Rationale: The correct answer is B: adolescents. Infectious mononucleosis is commonly caused by the Epstein-Barr virus, which is transmitted through saliva. Adolescents are more likely to engage in activities like kissing and sharing drinks, increasing the chances of virus transmission. Infants have maternal antibodies for protection, young adults may have developed immunity, and the elderly have had more exposure to the virus and may have built immunity over time.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Family Retroviridae is known for having a single-stranded RNA genome. 2. The (-) sign indicates that the RNA strand is negative-sense. 3. Therefore, the correct answer A, "Their capsid consists of two copies of ssRNA(-)," is accurate. Summary: - Choice B is incorrect because Retroviridae have simple type of symmetry. - Choice C is incorrect as Retroviridae are not enveloped viruses. - Choice D is incorrect because Retroviridae are enveloped viruses.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Tuberculosis, Q-fever, and Legionnaires disease all can infect the respiratory tract. Tuberculosis is a bacterial infection affecting the lungs, Q-fever is caused by a bacterium that primarily affects the lungs, and Legionnaires disease is a severe form of pneumonia. All three diseases specifically target the respiratory system, making them the correct choices. Choices A, B, and C are incorrect because each of them individually infects the respiratory tract, not just one or two of them.