ATI RN
Immune System Test Quizlet Questions
Question 1 of 5
The recirculation of naïve lymphocytes follows which sequential order?
Correct Answer: A
Rationale: The correct answer is A because naïve lymphocytes circulate through blood, enter lymph nodes (LN) via high endothelial venules (HEV), encounter antigens in LN, exit via efferent lymphatics, drain into the thoracic duct, and return to blood circulation. Choice B is incorrect because it skips the step of entering LN through HEV. Choice C is incorrect because it starts with inflammatory sites instead of blood, and it also lacks the step of entering LN through HEV. Choice D is incorrect as only option A correctly follows the sequential order of recirculation of naïve lymphocytes.
Question 2 of 5
Acquired immunity is a result of previous exposure
Correct Answer: B
Rationale: The correct answer is B: to vaccination. Acquired immunity is the immune response developed after exposure to a vaccine, which stimulates the immune system to recognize and remember specific pathogens. Vaccination helps the body build immunity without causing serious illness like choice A, without requiring repeated exposure like choice C, and without being related to treatment with penicillin like choice D. Vaccination mimics natural infection, prompting the body to produce memory cells that can respond more effectively when encountering the actual pathogen in the future.
Question 3 of 5
What is the medical term for an abnormal increase in white blood cells?
Correct Answer: A
Rationale: The correct answer is A: Leukocytosis. Leukocytosis refers to an abnormal increase in white blood cells, indicating an immune response. Thrombocytosis (B) is an increase in platelets, not white blood cells. Anemia (C) is a decrease in red blood cells. Hemolysis (D) is the breakdown of red blood cells, not related to an increase in white blood cells. Therefore, A is the correct answer as it specifically relates to an abnormal increase in white blood cells.
Question 4 of 5
Which of the following early contributors to the development of immunology is paired up properly with his or her accomplishment?
Correct Answer: D
Rationale: Rationale: Robert Koch is correctly paired with developing techniques to grow pure bacterial cultures. Koch's work laid the foundation for bacteriology and allowed for the isolation and identification of specific disease-causing bacteria. This technique, known as Koch's postulates, revolutionized the field of microbiology by linking specific pathogens to specific diseases. Summary: A: Louis Pasteur - Incorrect. While Pasteur is known for his work in vaccination and pasteurization, the provided accomplishment is associated with Edward Jenner, not Pasteur. B: Paul Ehrlich - Incorrect. Ehrlich is known for his work on immunology and coined the term "magic bullet," but he did not identify lymphocytes as cells mediating adaptive immunity. C: MacFarlane Burnet - Incorrect. Burnet is known for his clonal selection theory, not the side-chain theory of antibodies as described in the choice.
Question 5 of 5
A protein-protein interaction domain present both in TLR-4 and MyD88 is:
Correct Answer: B
Rationale: The correct answer is B: TIR. This is because both TLR-4 and MyD88 contain a Toll/interleukin-1 receptor (TIR) domain, which mediates protein-protein interactions in the Toll-like receptor signaling pathway. The other options, such as A (CARD), C (LRR), and D (Immunoglobulin-like domain), are not present in both TLR-4 and MyD88 and do not play a significant role in their interaction in the signaling pathway. This makes B the most appropriate choice as it accurately identifies the common protein-protein interaction domain between TLR-4 and MyD88.