The reasons determining bioavailability are:

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Safety Pharmacology Across the Lifespan ATI Quizlet Questions

Question 1 of 5

The reasons determining bioavailability are:

Correct Answer: C

Rationale: Bioavailability depends on absorption extent and hepatic first-pass metabolism (Choice C), where liver metabolism reduces drug availability post-oral administration. Blood rheology (Choice A) is unrelated, dose/intakes (Choice B) are factors but not primary, and filtration (Choice D) affects excretion.

Question 2 of 5

Metabolic transformation and conjugation usually results in an increase of a substance biological activity:

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Target proteins which a drug molecule binds are:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

All of the following statements about efficacy and potency are true EXCEPT:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

What is the type of drug-to-drug interaction which is the result of interaction at receptor, cell, enzyme or organ level?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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