The rate at which inhalational anaesthetic passes into tissues depends on

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Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions

Question 1 of 5

The rate at which inhalational anaesthetic passes into tissues depends on

Correct Answer: D

Rationale: The rate at which an inhalational anaesthetic reaches tissues is influenced by all the factors listed: the blood-tissue partition coefficient delivery rate and partial pressure.

Question 2 of 5

Which of the following drugs would be contraindicated for this patient with cogwheel rigidity and decreased dopamine metabolism in the striatum?

Correct Answer: B

Rationale: Carbidopa is a drug that inhibits the peripheral metabolism of levodopa, allowing more levodopa to reach the brain and be converted to dopamine. In this patient with decreased dopamine metabolism in the striatum, adding carbidopa to the regimen would further enhance the availability of levodopa in the brain, thereby improving symptoms of parkinsonism. The other options do not directly address the issue of decreased dopamine metabolism in the striatum.

Question 3 of 5

Which of the following effects most likely occurred during surgery?

Correct Answer: D

Rationale: The correct answer is D. Increased skeletal muscle tone, fever, skeletal muscle contractions, and diaphoresis are signs of malignant hyperthermia, a rare but life-threatening condition triggered by certain anesthesia agents like halothane and succinylcholine in susceptible individuals. This condition can lead to severe metabolic and respiratory acidosis, cardiac arrhythmias, and hyperkalemia.

Question 4 of 5

Morphine can be used for all the following therapeutic indications EXCEPT:

Correct Answer: B

Rationale: Morphine treats MI pain (choice A), postoperative pain (choice C), and pulmonary edema (choice D) by reducing pain and preload. Head injury pain (choice B) contraindicates it due to respiratory depression and ICP risks. This exception guides safe use.

Question 5 of 5

A 72-year-old man is brought to his physician by his son. The son complains that this patient has been becoming forgetful, confused, moody, and aggressive over the past few months. One drug that may be used to treat this patient's symptoms is donepezil. Which of the following describes an effect of donepezil?

Correct Answer: D

Rationale: Donepezil, a cholinesterase inhibitor, increases synaptic acetylcholine levels by preventing its breakdown, improving cognitive function in Alzheimer's disease.

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