ATI RN
Pediatric Immunizations NCLEX Questions Questions
Question 1 of 5
The processes of affinity maturation and class switching are used to generate a lower-affinity, less effective antibody molecule during the immune response.
Correct Answer: B
Rationale: Affinity maturation and class switching increase antibody affinity and effectiveness, not decrease.
Question 2 of 5
The membrane attack complex (MAC) uses C3 to activate the final part of the complement pathway. It is important in defense against Neisseria. Which of the following components is/are inserted into the plasma membrane of the target cell, allowing for free passage of water/solute and thus killing the cell?
Correct Answer: D
Rationale: C5b-C9 form the MAC, with C9 polymerizing to lyse the target cell.
Question 3 of 5
Increases marrow production of neutrophils
Correct Answer: C
Rationale: G-CSF stimulates neutrophil production in bone marrow.
Question 4 of 5
Increases vascular permeability
Correct Answer: B
Rationale: Histamine, released by mast cells, increases vascular permeability, aiding immune cell infiltration to the site of infection.
Question 5 of 5
Natural killer cell receptors NKG2/CD94 and killer inhibitory receptors allow for the killing of antibodies in the presence of:
Correct Answer: D
Rationale: NK cells kill when MHC class I is absent or reduced, as inhibitory receptors are not engaged.