ATI RN
Chapter 11 Cardiovascular Drugs Test Questions Quizlet Questions
Question 1 of 5
The principal mechanism of phentolamine-induced tachycardia is:
Correct Answer: A
Rationale: The correct answer is A because phentolamine is an alpha-adrenergic antagonist that blocks presynaptic alpha2 receptors. By inhibiting these receptors, it increases norepinephrine release, leading to stimulation of unblocked beta receptors on the heart, resulting in tachycardia. This mechanism directly links the action of phentolamine to the observed tachycardia. Choice B (Baroreflex mechanism) is incorrect because phentolamine-induced tachycardia is primarily mediated by the alpha2 receptor antagonism rather than the baroreflex mechanism. Choice C (Direct effect on the heart by stimulation of beta1 receptors) is incorrect because phentolamine does not directly stimulate beta1 receptors on the heart; rather, it indirectly causes cardiac stimulation through enhanced norepinephrine release. Choice D (Inhibition of transmitter reuptake at noradrenergic synapses) is incorrect because phentolamine does not inhibit
Question 2 of 5
Adverse effect caused by phenobarbital is:
Correct Answer: D
Rationale: The correct answer is D. Phenobarbital is a barbiturate medication that can cause physical and psychological dependence, leading to addiction (Choice A). It can also exacerbate petit mal epilepsy by lowering seizure threshold (Choice B). Additionally, sedation is a common side effect of phenobarbital due to its central nervous system depressant properties (Choice C). Therefore, all of the above choices are correct, making option D the correct answer.
Question 3 of 5
Indicate a selective inhibitor of monoamine oxidase B:
Correct Answer: D
Rationale: The correct answer is D: Selegiline. Selegiline is a selective inhibitor of monoamine oxidase B (MAO-B), which helps increase dopamine levels in the brain. Levodopa is a precursor to dopamine, Amantadine is an antiviral drug used to treat Parkinson's symptoms, and Tolcapone is a COMT inhibitor. Selegiline specifically targets MAO-B without affecting MAO-A, making it the most suitable choice for selective inhibition of MAO-B in the context of Parkinson's disease treatment.
Question 4 of 5
It is undesirable to take alcohol before going outdoors when it extremely cold, but it may be harmless to take some after coming into a warm place from the cold.
Correct Answer: A
Rationale: The correct answer is A: TRUE. Alcohol consumption before going outdoors in extremely cold weather can lead to increased risk of hypothermia as it dilates blood vessels and causes heat loss. However, after coming indoors from the cold, having some alcohol may not pose the same risk as the body is already in a warm environment and can regulate its temperature better. Therefore, it is important to avoid alcohol before exposure to cold but may be harmless after being in a warm place. Choices B, C, and D are incorrect because they do not accurately reflect the specific considerations related to alcohol consumption in cold weather.
Question 5 of 5
Indicate the antipsychotic drug ,which is a thioxanthene derivative:
Correct Answer: D
Rationale: The correct answer is D: Thiothixene. Thiothixene is a thioxanthene derivative due to its chemical structure containing a thioxanthene ring system. Haloperidol, Clozapine, and Chlorpromazine are not thioxanthene derivatives. Haloperidol is a butyrophenone, Clozapine is a dibenzodiazepine, and Chlorpromazine is a phenothiazine. Therefore, the correct choice is D as it is the only antipsychotic drug among the options that belongs to the thioxanthene class based on its chemical structure.