ATI RN
Learning Cardiovascular Drugs Pharmacology Questions
Question 1 of 5
The principal mechanism of fomepizol action is associated with inhibition of:
Correct Answer: C
Rationale: Certainly! The correct answer is C: Alcohol dehydrogenase. Fomepizole is used in treating methanol and ethylene glycol toxicity by inhibiting alcohol dehydrogenase, preventing the formation of toxic metabolites. This mechanism blocks the conversion of methanol and ethylene glycol into their toxic byproducts, formic acid, and glycolic acid, respectively. Choices A, B, and D are incorrect as fomepizole does not target aldehyde dehydrogenase, acetylcholinesterase, or monoamine oxidase in this context.
Question 2 of 5
Actoprotectors are:
Correct Answer: A
Rationale: The correct answer is A because actoprotectors are substances that improve physical efficiency by enhancing endurance, stamina, and overall physical performance. This is supported by scientific evidence showing their positive effects on exercise capacity and fatigue resistance. Choice B is incorrect because cognition enhancers focus on improving cognitive functions, not physical performance. Choice C is incorrect as actoprotectors do not raise non-specific resistance towards stresses but specifically target physical efficiency. Choice D is incorrect because actoprotectors do not directly stimulate respiratory and vasomotor centers in the brain, but rather enhance physical capabilities.
Question 3 of 5
Limitation of buspirone is:
Correct Answer: B
Rationale: Buspirone has a slow onset of action due to its mechanism of action involving serotonin and dopamine receptors. This makes it unsuitable for acute anxiety or panic attacks. The slow onset allows for gradual anxiolytic effects over time. Other choices are incorrect because buspirone has a wide therapeutic index, minimal potential for physical dependence, and does not typically impair mentation or motor functions.
Question 4 of 5
Which of the following inhaled anesthetics is an induction agent of choice in patient with airway problems?
Correct Answer: D
Rationale: The correct answer is D: None of the above. In patients with airway problems, the induction agent of choice is usually propofol. Desflurane (A) and nitrous oxide (B) are not ideal for patients with compromised airways due to their irritant properties and potential for airway reactivity. Halothane (C) is not recommended in patients with airway problems due to its potential for respiratory depression and airway irritation. Therefore, the correct choice is D as propofol is the preferred induction agent in patients with airway issues.
Question 5 of 5
Which drug is an analog of prostaglandin E1?
Correct Answer: A
Rationale: The correct answer is A: Misoprostol. Misoprostol is an analog of prostaglandin E1, as it shares similar pharmacological properties. Prostaglandin E1 helps protect the stomach lining and promotes healing of ulcers. Misoprostol, by mimicking prostaglandin E1, can be used to prevent and treat ulcers caused by NSAIDs. De-nol (B) and sucralfate (C) work differently by forming a protective barrier over ulcers. Omeprazole (D) is a proton pump inhibitor that reduces stomach acid production, not an analog of prostaglandin E1.