The primary mode of action of aminoglycosides is to:

Correct Answer: A

Rationale: Aminoglycosides primarily inhibit protein synthesis by binding to the 30S ribosomal subunit in bacteria. This action leads to misreading of mRNA and ultimately disrupts the translation process, resulting in faulty protein production and bacterial cell death. Incorrect choices: B: Aminoglycosides do not inhibit DNA replication. C: Aminoglycosides do not disrupt cell membrane integrity. D: Aminoglycosides do not inhibit folic acid synthesis. In summary, the correct choice (A) aligns with the known mechanism of action of aminoglycosides, making it the most appropriate answer.

Correct Answer: D

Rationale: The correct answer is D: Binary fission. Binary fission is a method of bacterial cell division, not a method of acquiring genetic material. Transformation, conjugation, and transduction are mechanisms through which bacteria can acquire genetic material from other sources. Transformation involves the uptake of naked DNA from the environment, conjugation is the transfer of genetic material through direct cell-to-cell contact, and transduction is the transfer of genetic material via bacteriophages. Therefore, binary fission is the only option that does not involve the acquisition of new genetic material.

Correct Answer: B

Rationale: The correct answer is B: Escherichia coli. E. coli is a common bacterium found in the gastrointestinal tract and is a leading cause of UTIs. It has specific virulence factors that enable it to adhere to and infect the urinary tract. Salmonella enterica causes food poisoning, Vibrio cholerae causes cholera, and Streptococcus pyogenes causes strep throat and skin infections, not UTIs. Therefore, B is the correct answer as it is the only bacterium known for causing UTIs.

Correct Answer: B

Rationale: The correct answer is B because anaerobic bacteria can grow in environments without oxygen. Anaerobic bacteria do not require oxygen for their metabolism and energy production. They can thrive in oxygen-deprived conditions by using alternative electron acceptors. Choice A is incorrect because anaerobic bacteria do not require oxygen to survive. Choice C is incorrect because anaerobic bacteria typically cannot survive in the presence of high concentrations of oxygen. Choice D is incorrect because anaerobic bacteria do not perform photosynthesis.

Correct Answer: B

Rationale: Step 1: Gram-negative, comma-shaped bacterium suggests a curved rod morphology, typical of Campylobacter jejuni. Step 2: Motility is a characteristic of Campylobacter species. Step 3: Campylobacter jejuni is a common cause of bacterial diarrhea in humans. Step 4: Vibrio cholerae causes cholera, not typically associated with comma-shaped morphology. Shigella dysenteriae and Escherichia coli are not comma-shaped.