The physician ordered a brand name drug for the client, paroxetine (Paxil). After taking this medication for a year, the client tells the nurse that it is no longer working. What is the best assessment of the nurse at this time?

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ATI Capstone Pharmacology Assessment 2 Quizlet Questions

Question 1 of 5

The physician ordered a brand name drug for the client, paroxetine (Paxil). After taking this medication for a year, the client tells the nurse that it is no longer working. What is the best assessment of the nurse at this time?

Correct Answer: B

Rationale: Paroxetine's effectiveness waning after a year suggests possible drug interactions reducing its levels or efficacy, a common issue needing assessment via medication review. Needing a change assumes a conclusion without evidence. Paxil and paroxetine are the same (brand vs. generic), making that question moot. Beck assessment evaluates depression, not drug failure. Interactions align with pharmacokinetic principles, offering a proactive step to identify culprits like enzyme inducers, critical for adjusting therapy.

Question 2 of 5

The patient has been receiving amitriptyline (Elavil) for 2 weeks. He tells the nurse he doesn't think this medicine is working, as he is still depressed. What is the best response by the nurse?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

A 48-year-old woman with 2-year history of rheumatoid arthritis has not had sufficient relief with methotrexate alone. Her physician prescribes a biologic TNF-α inhibitor that consists of a recombinant human IgG fused to TNF-α receptor. Which of the following drugs is this?

Correct Answer: C

Rationale: Rheumatoid arthritis (RA) progression despite methotrexate warrants a TNF-α inhibitor. The description-recombinant human IgG fused to TNF-α receptor-points to Etanercept . Adalimumab and Golimumab are monoclonal antibodies against TNF-α, not receptor fusions. Certolizumab is a PEGylated Fab fragment, not IgG-based. Etanercept , a fusion protein, binds TNF-α, neutralizing it, and matches the question's structure. Infliximab (E) is a chimeric antibody. Etanercept's unique receptor-IgG design distinguishes it, effectively reducing RA inflammation by sequestering TNF-α, a key cytokine, making it the precise answer here.

Question 4 of 5

A 52-year-old woman with a history of recurrent urinary tract infections complains of easy bruising as well as chronic fatigue. She is maintained on daily antibiotic prophylaxis with trimethoprim. Which of the following hematologic effects is likely as a result of long-term therapy with trimethoprim?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

A 29-year-old man who is a known alcoholic is able to purchase phencyclidine from another user of this substance. He takes a 'triple dose' of the substance. Which of the following effects is likely to be observed?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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