ATI RN
Pharmacology ATI Quizlet Questions
Question 1 of 5
The phenomenon in which two dugs produce opposite effects on a physiologic system but do not act at the same receptor site is?
Correct Answer: C
Rationale: In chemical antagonism, two drugs produce opposite effects on a physiological system but do not act at the same receptor site. This type of antagonism occurs when one drug chemically interacts with another drug to reduce its effects. The drugs involved in chemical antagonism do not compete for the same receptor site, unlike competitive antagonism where drugs compete for the same receptor site, or noncompetitive antagonism where drugs may act at different sites but still result in inhibition. Physiological antagonism involves two drugs that produce opposite effects but do not necessarily interact chemically. Potentiation refers to the increase in effect when two drugs are combined. Given the scenario described in the question, the phenomenon of two drugs producing opposite effects without acting at the same receptor site best aligns with chemical antagonism.
Question 2 of 5
Which of the following is suitable for immediate treatment of an 18-year-old woman presenting with weight loss, tachycardia and a goitre?
Correct Answer: D
Rationale: Weight loss, tachycardia, and goitre suggest hyperthyroidism (e.g., Graves'). Verapamil controls rate but not thyroid function. Radioactive iodine (131I) treats long-term, not immediately. Carbamazepine is for seizures, L-thyroxine worsens hyperthyroidism. Atenolol, a beta-blocker, immediately reduces tachycardia and symptoms by blocking adrenergic effects, suitable for acute management while awaiting antithyroid drugs (e.g., propylthiouracil). Its symptomatic relief is critical in hyperthyroid crises.
Question 3 of 5
Which is appropriate nursing care for a patient receiving total parenteral nutrition (TPN) in an acute care setting? (Select all that apply.)
Correct Answer: A
Rationale: Monitoring blood glucose (A) is critical because TPN can cause hyperglycemia. Measuring intake and output (B) helps assess fluid balance. Monitoring the insertion site (D) is essential to detect infection or infiltration. Blood should never be administered through the TPN line (C) due to risk of contamination.
Question 4 of 5
The patient has been receiving amitriptyline (Elavil) for 2 weeks. He tells the nurse he doesn't think this medicine is working, as he is still depressed. What is the best response by the nurse?
Correct Answer: A
Rationale: Amitriptyline, a tricyclic antidepressant, typically requires 2 to 6 weeks to achieve full therapeutic effect, as it gradually increases neurotransmitter levels (e.g., serotonin, norepinephrine) in the brain to alleviate depression. After only 2 weeks, the patient's continued symptoms are expected, not indicative of failure, making choice A the best response: it educates the patient on the timeline, fostering adherence. Choice B dismisses the patient's feelings with subjective reassurance, undermining trust. Choice C prematurely suggests switching drugs without evidence, risking unnecessary changes. Choice D exaggerates the timeline to months, which is inaccurate and discouraging. The nurse's role is to provide accurate information and support, reinforcing that delayed onset is normal for this class of medication, thus making choice A the most therapeutic and evidence-based response.
Question 5 of 5
When reviewing the health history of a patient, the nurse will note that a potential contraindication to potassium supplements exists if the patient has which problem?
Correct Answer: C
Rationale: Potassium supplements are contraindicated in patients with renal disease because impaired kidney function can lead to the inability to adequately excrete potassium. This can result in potentially dangerous hyperkalemia (high potassium levels) in the bloodstream, which can cause serious cardiac dysrhythmias. Therefore, patients with renal disease should be cautious when taking potassium supplements or may need to avoid them altogether to prevent complications.